T Robak 1
1. Pracownia Farmakologii Klinicznej Zakładu Farmakologii, Akademii Medycznejw Lodzi.
Published:
GICID: 01.3001.0000.2876
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1991; 45 (5)
Abstract
In the paper the possible physiological significance and pathological role of cachectin as a mediator of endotoxic shock and wasting in chronic diseases are reviewed. The influence of this monokine on normal haematopoietic cells and their leukaemic counterparts is presented. The effect of TNF on neoplastic cells in vitro and in vivo and its possible application in the treatment of cancer is also discussed.