K Komosińska 1 , K Olczyk
1. Katedra i Zakład Chemii Klinicznej i Diagnostyki Laboratoryjnej Slaskiej AkademiiMedycznej w Sosnowcu.
Published:
GICID: 01.3001.0000.3063
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1995; 49 (6)
Abstract
The role of free radicals as well as cytokines (IL-1, tumor necrosis factor alpha, interferon gamma) and nitric oxide in the immune-mediated processes leading to the beta-cell destruction during IDDM is described. It is also pointed that the excess of IL-1ra in relation to IL-1 prevents IL-1 toxicity to beta-cells.