K Komosińska 1 , K Olczyk , K Winsz
1. Katedra i Zakład Chemii Klinicznej i Diagnostyki Laboratoryjnej Slaskiej AkademiiMedycznej w Sosnowcu.
Published:
GICID: 01.3001.0000.3134
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1997; 51 (3)
Abstract
This article reviews the current concept in the ethiology and pathogenesis of systemic sclerosis. It is suggested that free radicals play a crucial role in pathomechanisms of scleroderma. In addition, the influence of some environmental agents (silica, bleomycin, alcohol, toxic oil) on free radical production and subsequent induction of scleroderma or scleroderma-like syndrome is also described.