REVIEW ARTICLE
[Various functions of human erythrocyte membrane lipids]
R Bucki 1 , J C Sulpice , F Giraud , J Górski
1. Zakład Fizjologii Akademii Medycznej w Białymstoku.
Published:
GICID: 01.3001.0000.3156
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1997; 51 (6)
Abstract
The major phospholipid classes of the human red blood cell membrane are: phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine and sphingomyelin. These phospholipids are distributed asymmetrically across the two halves of the lipid bilayer. This asymmetry appears to be generated and maintained by an ATP-dependent translocation of aminophospholipids from outer to inner leaflet, and by the interaction of phospholipids with skeletal proteins. The phosphoinositides account for 3-4% of total erythrocyte membrane phospholipid. They play an important role in signal transduction and are involved in other various membrane functions.