COMMENTARY ON THE LAW
[Endogenous retroviral sequences present in the human genome]
T Kubiatowski 1 , U Gasowska-Giszczak , M Grabek-Gawłowicz , J Wojcierowski
1. Zakład Genetyki Medycznej Akademii Medycznej w Lublinie.
Published:
GICID: 01.3001.0000.3172
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1998; 52 (3)
Abstract
The human genome contains a variety of elements resembling mammalian retroviruses. Most of these sequences are related to primate, murine C-types viruses, murine B-type viruses and A-type particles or HTLV. These sequences comprise at least 0.1-0.6% of human genome. They are transcriptionally active especially in human placenta, embryonic tissue and in human tumor cell lines. Endogenous retroviruses and retroviral elements represent a cellular reservoir of possibly pathogenic retroviral genes.