A Szuster-Ciesielska 1 , M Kandefer-Szerszeń
1. Zakład Wirusologii i Immunologii, Instytutu Mikrobiologii i Biotechnologii,Uniwersytetu Marii Curie-Skłodowskiej w Lublinie.
Published:
GICID: 01.3001.0000.3199
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1999; 53 (1)
Abstract
The article reviews the literature with regard to identification of lymphocyte subsets that respond to specific inducers and produce IFN-gamma, the structure of IFN-gamma gene, the IFN signal transduction pathway that initiates biochemical changes at cellular level and influences the function of immunocompetent cells: mononuclear phagocytes, T and B lymphocytes. The interaction of IFN-gamma with other cytokines in regulation of immune response is also discussed.