A Teisseyre 1
1. Katedra i Zakład Biofizyki, Akademii Medycznej we Wrocławiu.
Published:
GICID: 01.3001.0000.3226
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1999; 53 (2)
Abstract
This review focuses on biophysical properties and physiological role of voltage-gated potassium channels (named as Kv1.3) in T lymphocytes. In the first section basic electrophysiological and pharmaceutical properties of the channels have been described. Then the data on the role of the channels in setting the cell resting membrane potential, cell mitogenesis and volume regulation has been reviewed. Finally, results on patch-clamp studies on the changes in the channel expression in TL in patients suffering from chronic renal failure have been presented.