[Activation mechanisms, biological role and inhibitors of metalloproteases in the extracellular matrix]

REVIEW ARTICLE

[Activation mechanisms, biological role and inhibitors of metalloproteases in the extracellular matrix]

M Gacko 1

1. Klinika Chirurgii Naczyń i Transplantacji Akademii Medycznej w Białymstoku.

Published:

GICID: 01.3001.0000.3334

Available language versions: en pl

Issue: Postepy Hig Med Dosw 2001; 55 (2)

Abstract

Prometalloproteinases are activated by serine proteases, MMP-3, leucocytic elastase, furin, furin-like proteases and by membrane-type metalloproteinases as well. They form complexes with some proMMPs and thus they modify their activation.

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