Magdalena Przybysz , Iwona Kątnik-Prastowska
Published: 2001-09-15
GICID: 01.3001.0000.3469
Available language versions: en
Issue: Postepy Hig Med Dosw 2001; 55 (5)
Abstract
Fibronectin is an extracellular matrix component which appears in different isiforms, due to alternative mRNA splicing of the ED-A, ED-B and III-CS regions and subsequent post-translational modification. It is composed of multiple homologous repeats and contains many functional domains. Because of its ability to interact with many ligands icluding cells, heparin, fibrin, collagen, DNA, immunoglobulin, fibronectin can play the role in variety of biological processes