COMMENTARY ON THE LAW

Multilevel regulation of the tyrosine hydroxylase. I.Posttranscriptional levels

Robert Lenartowski , Anna Goc

Published: 2002-07-15

GICID: 01.3001.0000.3519

Available language versions: en

Issue: Postepy Hig Med Dosw 2002; 56 (4)

Abstract

The tyrosine hydroxylase plays a key role in the catecholamine synthesis responding to many stimuli disturbing homeostasis. In this part we described the posttranscriptional levels of the gene and the protein regulation including: alternative splicing, isoform specificity, feedback inhibition, protein phosphorylation and dephosphorylation, protein stability, translational regulation.