Katarzyna Zielińska-Kuźniarz , Małgorzata Mieszała , Tomasz Lipiński , Andrzej Gamian
Published: 2003-09-15
GICID: 01.3001.0000.3552
Available language versions: en
Issue: Postepy Hig Med Dosw 2003; 57 (5)
Abstract
The aminoacylation of bacterial polysaccharide antigens and the biological role of this phenomenon are poorly understood, although it might be relevant in the processes of the infection and immunity. Due to the lability of ester linked substituens on glycoconjugate antigens, usually such groups escaped detection during routine strustural investigation. Among the only few data available, these on the occurrence of glycine in endotoxic lipopolysaccharides of Gram-negative bacteria are well documented. This work summarises these data on glycine as an integral constituent of bacterial LPS and also on some other amino acid esters in teichoic acids and phosphatidylglycerol of Gram-positive bacteria.The possible functions are discucced of such noncarbohydrate ester linked substituets in bacterial antigens