The role of diet in multiple sclerosis
Klaudia Konikowska 1 , Bożena Regulska-Ilow 1Abstract
Multiple sclerosis is a demyelinating disease of the central nervous system, occurs most commonly in adults between 20 and 40 years of age. Etiology of this disease is still not known, and one of the analyzed environmental factors is food. In this study, based on literature, discusses the impact of dietary intake of food on the occurrence and development of the disease. This study demonstrated that patients with multiple sclerosis less than healthy people ate bread and cereal products, fish, some vegetables and fruits. While patients often consumed an animal products, whole milk and sweets. It also discusses Swank’s diet, which suggest that the severity of symptoms disease may be responsible food of animal origin, which is rich in saturated fatty acids. The author found that patients who comply a diet, after 34 years of application, the risk of death due to multiple sclerosis was three times lower than in those who have not complied with all the dietary recommendations. Moreover, research demonstrated a correlation between deficiency of omega-3, vitamin D, B12, antioxidant vitamins and folic acid in diet, and the development and exacerbation of symptoms of multiple sclerosis. Results of research concerning the relationship between dietary factors and the occurrence and development of this disease are inconclusive why the need is greater the amount thereof in this field. Patients may consider using a diet or supplements, if pharmacotherapy and other alternative and complementary methods do not bring expected effects.
References
- 1. About the Swank low-fat diet for the treatment of MS. http://www.swankmsdiet.org/About%20The%20Diet (02.04.2012)
Google Scholar - 2. Andersen R., Mølgaard C., Skovgaard L.T., Brot C., Cashman K.D.,Chabros E., Charzewska J., Flynn A., Jakobsen J., Kärkkäinen M., KielyM., Lamberg-Allardt C., Moreiras O., Natri A.M., O’Brien M., RogalskaNiedzwiedzM., Ovesen L.: Teenage girls and elderly women livingin northern Europe have low winter vitamin D status. Eur. J. Clin.Nutr., 2005; 59: 533-541
Google Scholar - 3. Ascherio A., Munger K.L.: Environmental risk factors for multiplesclerosis. Part II: Noninfectious factors. Ann. Neurol., 2007;61: 504-513
Google Scholar - 4. Baranzini S.E., Galwey N.W., Wang J., Khankhanian P., LindbergR., Pelletier D., Wu W., Uitdehaag B.M., Kappos L., GeneMSA Consortium,Polman C.H., Matthews P.M., Hauser S.L., Gibson R.A., OksenbergJ.R., Barnes M.R.: Pathway and network-based analysis ofgenome-wide association studies in multiple sclerosis. Hum. Mol.Genet., 2009; 18: 2078-2090
Google Scholar - 5. Besler H.T., Comoğlu S.: Lipoprotein oxidation, plasma total antioxidantcapacity and homocysteine level in patients with multiplesclerosis. Nutr. Neurosci., 2003; 6: 189-196
Google Scholar - 6. Besler H.T., Comoğlu S., Okcu Z.: Serum levels of antioxidant vitaminsand lipid peroxidation in multiple sclerosis. Nutr. Neurosci.,2002; 5: 215-220
Google Scholar - 7. Bolesławska I., Grygiel-Górniak B., Przysławski J.: Żywienioweaspekty rozwoju osteoporozy wśród kobiet i mężczyzn z regionuWielkopolski. Now. Lek., 2006; 75: 27-30
Google Scholar - 8. Cameron M.H., Lord S.: Postular control in multiple sclerosis:implications for fall prevention. Curr. Neurol. Neurosci. Rep., 2010;10: 407-412
Google Scholar - 9. Charzewska J., Weker H.: Ogólnopolskie badanie nad zawartościąwapnia i witaminy D w dietach dzieci w wieku 4 lat. Pediatr. Współcz.Gastroenter., 2006; 8: 107-109
Google Scholar - 10. Compston A., Coles A.: Multiple sclerosis. Lancet, 2002; 359:1221-1231
Google Scholar - 11. de Bustos F., Jiménez-Jiménez F.J., Molina J.A., Gómez-EscalonillaC., de Andrés C., del Hoyo P., Zurdo M., Tallón-Barranco A., BerbelA., Porta-Etessam J., Parrilla G., Arenas J.: Serum levels of coenzymeQ10 in patients with multiple sclerosis. Acta Neurol. Scand.,2000; 101: 209-211
Google Scholar - 12. Dworzańska E., Mitosek-Szewczyk K., Stelmasiak Z.: Zespół zmę-czenia w stwardnieniu rozsianym. Neurol. Neurochir. Pol., 2009;43: 71-76
Google Scholar - 13. Fryze W., Mirowska-Guzel D., Wiszniewska M., Darda-Ledzion L.,Członkowski A., Członkowska A.: Alternative methods of treatmentused by multiple sclerosis patients in Poland. Neurol. Neurochir.Pol., 2006; 40: 386-390
Google Scholar - 14. Ghadirian P., Jain M., Ducic S., Shatenstein B., Morisset R.: Nutritionalfactors in the aetiology of multiple sclerosis: a case-controlstudy in Montreal, Canada. Int. J. Epidemiol., 1998; 27: 845-852
Google Scholar - 15. Hadžović-Džuvo A., Lepara O., Valjevac A., Avdagić N., Hasić S.,Kiseljaković E., Ibragić S., Alajbegović A.: Serum total antioxidantcapacity in patients with multiple sclerosis. Bosn. J. Basic Med. Sci.,2011; 11: 33-36
Google Scholar - 16. Jaśkiewicz E.: Epitopy na białkach mieliny rozpoznawane przezautoprzeciwciała obecne u chorych na stwardnienie rozsiane.Postępy Hig. Med. Dośw., 2004; 58: 472-482
Google Scholar - 17. Kampman M.T., Wilsgaard T., Mellgren S.I.: Outdoor activitiesand diet in childhood and adolescence relate to MS risk above theArctic Circle. J. Neurol., 2007; 254: 471-477
Google Scholar - 18. Kierzek A.: Benni, Babiński, Bouchard, Charcot. Ich wkład dorozwoju stosunków XIX-wiecznej medycyny polskiej i francuskiej.Przegl. Lek., 2007; 64: 183-184
Google Scholar - 19. Krótkie fakty o SM. Multiple Sclerosis International Federation.http:www.msif.org/pl/quick_facts/index.html (02.04.2012)
Google Scholar - 20. Leong E.M., Semple S.J., Angley M., Siebert W., Petkov J., McKinnonR.A.: Complementary and alternative medicines and dietaryinterventions in multiple sclerosis: what is being used in South Australiaand why? Complement. Ther. Med., 2009; 17: 216-223
Google Scholar - 21. Mahon B.D., Gordon S.A., Cruz J., Cosman F., Cantorna M.T.: Cytokineprofile in patients with multiple sclerosis following vitaminD supplementation. J. Neuroimmunol., 2003; 134: 128-132
Google Scholar - 22. Miller A., Korem M., Almog R., Galboiz Y.: Vitamin B12, demyelination,remyelination and repair in multiple sclerosis. J. Neurol.Sci., 2005; 233: 93-97
Google Scholar - 23. Miller E., Mrowicka M., Żołyński K., Kędziora J.: Stres oksydacyjnyw stwardnieniu rozsianym. Pol. Merkur. Lekarski, 2009; 27: 499-502
Google Scholar - 24. Mirzaei F., Michels K.B., Munger K., O’Reilly E., Chitnis T., FormanM.R., Giovannucci E., Rosner B., Ascherio A.: Gestational vitaminD and the risk of multiple sclerosis in offspring. Ann. Neurol.,2011; 70: 30-40
Google Scholar - 25. Munger K.L., Chitnis T., Frazier A.L., Giovannucci E., SpiegelmanD., Ascherio A.: Dietary intake of vitamin D during adolescence andrisk of multiple sclerosis. J. Neurol., 2011; 258: 479-485
Google Scholar - 26. Nordvik I., Myhr K.M., Nyland H., Bjerve K.S.: Effect of dietaryadvice and n-3 supplementation in newly diagnosed MS patients.Acta Neurol. Scand., 2000; 102: 143-149
Google Scholar - 27. Nortvedt M.W., Riise T., Mæland J.G.: Multiple sclerosis andlifestyle factors: the Hordaland Health Study. Neurol. Sci., 2005;26: 334-339
Google Scholar - 28. Pekmezovic T.D., Kisic Tepavcevic D.B., Mesaros S.T., DujmovicBasuroski I.B., Stojsavljevic N.S., Drulovic J.S.: Food and dietary patternsand multiple sclerosis: a case-control study in Belgrade (Serbia).Ital. J. Public Health, 2009; 6: 81-87
Google Scholar - 29. Ramagopalan S.V., Dyment D.A., Guimond C., Orton S.M., YeeI.M., Ebers G.C., Sadovnick A.D.: Childhood cow’s milk allergy andthe risk of multiple sclerosis: a population based study. J. Neurol.Sci., 2010; 291: 86-88
Google Scholar - 30. Ramagopalan S.V., Sadovnick A.D.: Epidemiology of multiplesclerosis. Neurol. Clin., 2011; 29: 207-217
Google Scholar - 31. Ramsaransing G.S., Fokkema M.R., Teelken A., Arutjunyan A.V.,Koch M., De Keyser J.: Plasma homocysteine levels in multiple sclerosis.J. Neurol. Neurosurg. Psychiatry, 2006; 77: 189-192
Google Scholar - 32. Ramsaransing G.S., Mellema S.A., De Keyser J.: Dietary patternsin clinical subtypes of multiple sclerosis: an exploratory study. Nutr.J., 2009; 8: 36
Google Scholar - 33. Risberg G., Aarseth J.H., Nyland H., Lauer K., Myhr K.M., MidgardR.: Prevalence and incidence of multiple sclerosis in OpplandCounty: a cross-sectional population-based study in a landlockedcounty of Eastern Norway. Acta Neurol. Scand., 2011; 124: 250-257
Google Scholar - 34. Swank R.L., Dugan B.B.: Effect of low saturated fat diet in earlyand late cases of multiple sclerosis. Lancet, 1990; 336: 37-39
Google Scholar - 35. Swank R.L., Goodwin J.: Review of MS patient survival ona Swank low saturated fat diet. Nutrition, 2003; 19: 161-162
Google Scholar - 36. Triantafyllou N., Evangelopoulos M.E., Kimiskidis V.K., KararizouE., Boufidou F., Fountoulakis K.N., Siamouli M., Nikolaou C., SfagosC., Vlaikidis N., Vassilopoulos D.: Increased plasma homocysteinelevels in patients with multiple sclerosis and depression. Ann. Gen.Psychiatry, 2008; 7: 17
Google Scholar - 37. van der Mei I.A., Ponsonby A.L., Dwyer T., Blizzard L., SimmonsR., Taylor B.V., Butzkueven H., Kilpatrick T.: Past exposure to sun,skin phenotype, and risk of multiple sclerosis: case-control study.BMJ, 2003; 327: 316
Google Scholar - 38. Weinstock-Guttman B., Baier M., Park Y., Feichter J., Lee-KwenP., Gallagher E., Venkatraman J., Meksawan K., Deinehert S., PendergastD., Awad A.B., Ramanathan M., Munschauer F., Rudick R.:Low fat dietary intervention with ω-3 fatty acid supplementationin multiple sclerosis patients. Prostaglandins Leukot. Essent. FattyAcids, 2005; 73: 397-404
Google Scholar - 39. Willer C.J., Dyment D.A., Sadovnick A.D., Rothwell P.M., MurrayT.J., Ebers G.C.; Canadian Collaborative Study Group: Timing ofbirth and risk of multiple sclerosis: population based study. BMJ,2005; 330: 120
Google Scholar - 40. Wingerchuk D.M., Lesaux J., Rice G.P., Kremenchutzky M., EbersG.C.: A pilot study of oral calcitriol (1,25-dihydroxyvitamin D3) forrelapsing-remitting multiple sclerosis. J. Neurol. Neurosurg. Psychiatry,2005; 76: 1294-1296
Google Scholar - 41. Yadav V., Shinto L., Morris C., Senders A., Baldauf-Wagner S.,Bourdette D.: Use and self-reported benefit of complementary andalternative medicine among multiple sclerosis patients. Int. J. MSCare, 2006; 8: 5-10
Google Scholar - 42. Zhang S.M., Hernán M.A., Olek M. J., Spiegelman D., Willett W.C.,Ascherio A.: Intakes of carotenoids, vitamin C, and vitamin E and MSrisk among two large cohorts of women. Neurology, 2001; 57: 75-80
Google Scholar