[2-Acetylaminofluorene–a model mutagen and hepatocarcinogen. Characterization of its interactions with DNA]

P Widłak ¹

1. Zakład Biologii Nowotworów Instytutu Onkologii, Gliwicach.

Published:

GICID: 01.3001.0000.2784

Available language versions: en pl

Issue: Postepy Hig Med Dosw 1992; 46 (5)

Abstract

2-Aminofluorene and its derivative 2-acetylaminofluorene are well known mutagens and carcinogens. Molecular mechanisms concerning their mutagenic and cancer promotion activity during hepatocarcinogenesis are summarized in the paper.