[Acute noninflammatory renal failure. New pathogenetic aspects in light of findings obtained in autopsy and biopsy of kidneys]

A Bohle ¹ , F Kokot , H Osswald , B Schubert , M Wehrmann , C Erley , T Risler

1. Instytut Patologii Uniwersytetu w Tybindze, Niemcy.

Published:

GICID: 01.3001.0000.2836

Available language versions: en pl

Issue: Postepy Hig Med Dosw 1994; 48 (2)

Abstract

Thorough studies of kidney specimens obtained at autopsy or by renal biopsy revealed, that in noninflammatory acute renal failure oliguria/anuria is caused by increased activation o the renal renin-angiotensin system and increased generation of adenosine. At the polyuric phase moderately increased adenosine in kidney tissue seems to be the main factor responsible for decreased glomerular filtration.