H Berbeć 1
1. Katedra i Zakład Chemii Fizjologicznej Akademii Medycznej w Lublinie.
Published:
GICID: 01.3001.0000.3133
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1997; 51 (3)
Abstract
Recent knowledge about biological role of tumor suppressor genes and their products: RB1, p53, WT1, DCC, APC/FAP, NF1, NF2, VHL, MCC and MTS1 is presented. The main approaches of these agents as physiological regulators of cell growth and proliferation are discussed. Views on the tumor suppressor genes involvement in the development of inherited and sporadic forms of cancer have been reviewed.