A Orzechowski 1 , T Motyl , T Płoszaj
1. Katedra Fizjologii Zwierzat, Wydziału Weterynaryjnego Szkoły Głównej GospodarstwaWiejskiego w Warszawie.
Published:
GICID: 01.3001.0000.3183
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1998; 52 (4)
Abstract
In this paper regard was put on contemporary matters related to apoptosis of myogenic cells of different types (myocardium, visceral, skeletal muscle) and updated theories on the action mechanisms of free radicals and their contribution to this process. Concern was put on the activity of certain growth factors and antioxidants belonging to group of polyphenols on the extent of apoptosis in myoblasts held in culture. Similarities between the pathways depicting the process of muscle differentiation and resistance to programmed cell death are presented. The concept of myogenic cell differentiation and implications to apoptosis induced by particular oxidants is extensively discussed.