W Lutz , W Sułkowski
Published:
GICID: 01.3001.0000.2706
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1989; 43 (5-6)
Abstract
The paper presents the general data concerning cytochrome P-448, as well as its participation in the formation of oxygen radicals and active metabolic intermediates, originated during xenobiotics’ oxidation. Also, induction of synthesis of cytochrome P-448 (aromatic hydrocarbons hydroxylase), along with the role this phenomenon plays in the initiation of neoplastic process, are discussed.