Ryszard Międzybrodzki
Published: 2003-11-15
GICID: 01.3001.0000.3560
Available language versions: en
Issue: Postepy Hig Med Dosw 2003; 57 (6)
Abstract
The isothiazole ring was first synthesized in 1956 by Adams and Slack. It was known earlier in condensed structures such as benzisothiazole (saccharin for example). The first found natural origin isothiazole derivative was brassilexin – a phytoalexin from Brassica juncea. In this review diverse biological activity of isothiazole derivatives and their application has been presented.