T Robak 1
1. II Klinika Chorób Wewnetrznych Akademii Medycznej w Lodzi.
Published:
GICID: 01.3001.0000.3035
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1995; 49 (2)
Abstract
The paper presents the molecular biology and biological activity of IL-1 alpha, IL-1 beta and IL-1 receptor antagonist. The role of IL-1 family in pathogenesis of a various disease including myeloid leukemias and other neoplastic diseases, diabetes mellitus, inflammatory diseases, sepsis syndrome and atherosclerosis is presented. Potential therapeutic value of IL-1 and IL-1 receptor antagonist is also discussed.