Anna Bilska , Lidia Włodek
Published: 2002-03-15
GICID: 01.3001.0000.3493
Available language versions: en
Issue: Postepy Hig Med Dosw 2002; 56 (2)
Abstract
Lipoic acid is a prostetic group of H-protein of the glycine cleavage system and the dihydrolipoamide acyltransferases (E2) of the pyruvate, alpha-ketoglutarate and branched-chain alpha-keto acid dehydrogenase complexes. Lipoic acid and its reduced form, dihydrolipoic acid, reacts with oxygen reactive species. This paper reviews the beneficial effects in oxidative stress models or clinical conditions.