[Diversity of signal transduction pathways which induce apoptosis of thymocytes. Role of bcl-2, pim-1, c-myc and p53 genes in selection processes of thymocytes]

J Matuszyk ¹ , L Strzadała

1. Laboratorium Immunologii Komórkowej Instytutu Immunologii i Terapii DoświadczalnejPAN we Wrocławiu.

Published:

GICID: 01.3001.0000.3005

Available language versions: en pl

Issue: Postepy Hig Med Dosw 1994; 48 (6)

Abstract

There are independent signaling pathways which transmit apoptotic signals in thymocytes. c-Myc and p53 proteins participate in the apoptosis induction, whereas Bcl-2 and Pim-1 proteins inhibit complex apoptotic machinery.