e of Wnt signaling and APC protein in the etiology of colorectal cancer

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e of Wnt signaling and APC protein in the etiology of colorectal cancer

Małgorzata Cebrat Leon Strządała

Published: 2001-07-15

GICID: 01.3001.0000.3458

Available language versions: en

Issue: Postepy Hig Med Dosw 2001; 55 (4)

Abstract

In this paper we present recent data on molecular function of APC protein and Wnt signaling pathway. Role of a link between APC and Wnt signaling in the etiology of colorectal cancer as well as significance of a mutant APC mice as a model of cancer in man are discussed.

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