COMMENTARY ON THE LAW

Effect of luliberin and its analogs on immunological system

Ewa Kurowska , Wojciech Gorczyca , Apolinary Szewczuk

Published: 2000-11-15

GICID: 01.3001.0000.3306

Available language versions: en

Issue: Postepy Hig Med Dosw 2000; 54 (6)

Abstract

Luliberin – luteinizing hormone-releasing hormone (LHRH) is the first link in hypothalamus-pituitary-gonads axis which participates in reproduction. This hormone and lutropin are released from immunological cells, however antagonists of LHRH inhibit this action. Some cytokines (IL-1b, GM-CSF) inhibit release of LHRH and other (IL-6, INF-g) stimulate this release.