[Factors stimulating and/or inhibiting growth processes of the adrenal cortex. I. The role of the anterior pituitary and hypothalamic hormones, insulin, sex steroids and certain neuropeptides]

M Szkudliński ¹ , A Lewiński , E Sewerynek , E Wajs

1. Instytut Endokrynologii Akademii Medycznej w Lodzi.

Published:

GICID: 01.3001.0000.2879

Available language versions: en pl

Issue: Postepy Hig Med Dosw 1991; 45 (5)

Abstract

This paper summarizes the recent knowledge on the factors stimulating or inhibiting the adrenocortical growth. In the part I of the present review the following stimulatory growth factors are discussed: ACTH–in vivo, N-POMC derivatives, dibutyryl cAMP–in vivo, GH, Prl, vasopressin, oxytocin, insulin, insulin-like growth factor I (somatomedin C), estradiol and vasoactive intestinal polypeptide (VIP). Among the factors, which inhibit the adrenocortical growth, the following ones are considered: ACTH–in vitro, cAMP–in vitro, adrenal steroids and testicular androgens. The remaining hormones and factors affecting the adrenocortical growth are described in the part II of the review.