E Paradowska 1
1. Laboratorium Wirusologii, Zakład Immunologii Chorób Zakaźnych.
Published:
GICID: 01.3001.0000.3025
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1995; 49 (1)
Abstract
A placenta constitutes a specific immune system that can protect a fetus against viral infections. We examined TNF, IFN and IL-6 production in organ cultures of human placenta and amniotic membrane. VSV replication and the cytokine production (TNF, IFN, IL-6) by human umbilical cord vein organ cultures and isolated endothelial cells were compared. We suggest that the local production of cytokines is responsible for the antiviral activity of placenta and endothelium.