A Plewka 1 , D Plewka , M Kamiński
1. II Katedra Histologii i Embriologii Slaskiej Akademii Medycznej w Katowicach.
Published:
GICID: 01.3001.0000.2857
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1994; 48 (4)
Abstract
In this paper we showed age effect on hepatic level of cytochrome P-450. We discussed effects of inductors on this hemoprotein also. Cytochrome P-450 content increased to 1-month of life, but decreased to 4-month. In the oldest rats cytochrome P-450 increased again. Content of this hemoprotein was induced by phenobarbital and beta-naphthoflavone in all examined groups, especially strong in young animals. Induction effect of dexamethasone was observed in 4-20-month of life.