Adam Opolski , Joanna Wietrzyk
Published: 2001-05-15
GICID: 01.3001.0000.3449
Available language versions: en
Issue: Postepy Hig Med Dosw 2001; 55 (3)
Abstract
The role of angiogenesis in tumor growth and metastasis is discussed. The endogenous activators and inhibitors of tumor angiogenesis are presented and their mechanisms of action are reviewed. An overview on angiogenesis as a new potential targed of antitumor therapy is described. The clinical trials of various antiangiogenic agents are briefly summarized and their differential mechanisms of action are discussed.