[Initiation of DNA replication in Streptomyces; organizational comparison of the oriC region in prokaryotic organisms]

J Zakrzewska-Czerwińska

Published:

GICID: 01.3001.0000.3026

Available language versions: en pl

Issue: Postepy Hig Med Dosw 1995; 49 (1)

Abstract

DnaA protein and its binding sequence (DnaA-box) are two elements essential for the initiation of chromosomal replication in Escherichia coli and other bacteria. Recently these two elements have been found to be conserved in four Gram-positive bacteria (Bacillus subtilis, Micrococcus luteus, Mycoplasma capricolum and Streptomyces lividans). The structures of eubacterial DnaA-box regions and their locations on the chromosome and than functional aspects od DnaA protein have been compared.