Interleukin-12 (IL-12) and its receptor

Jacek Szeliga Teresa Gościcka

Published: 2002-03-15

GICID: 01.3001.0000.3492

Available language versions: en

Issue: Postepy Hig Med Dosw 2002; 56 (2)


Abstract

This article reviews of recent data on the structure of IL-12 and the function of its receptor (IL-12R). It presents a new opinion on the role of its subunits in the cytokine activity and on the signal transmission via IL-12R in the process of cell activation by IL-12.

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