COMMENTARY ON THE LAW

Mitochondrial ion channels

Grazyna Debska , Anna Kicińska , Jolanta Skalska , Vladimir Berest , Adam Szewczyk

Published: 2002-05-15

GICID: 01.3001.0000.3501

Available language versions: en

Issue: Postepy Hig Med Dosw 2002; 56 (3)

Abstract

Ion channels selective for potassium or chloride ions are present in inner mitochondrial membranes. They are probably important in cellular events such as regulation of organelle volume changes. Additionally, mitochondrial potassium channels are targets for potassium channel openers and antidiabetic sulfonylureas. This review describes properties, and current hypotheses concerning the functional role of mitochondrial ion channels.