Non-nutritional use of breast milk

ORIGINAL ARTICLE

Non-nutritional use of breast milk

Magdalena Maria Piskorska-Jasiulewicz 1 , Małgorzata Witkowska-Zimny 1

1. Zakład Biofizyki i Fizjologii Człowieka, Warszawski Uniwersytet Medyczny,

Published: 2017-10-04
DOI: 10.5604/01.3001.0010.5049
GICID: 01.3001.0010.5049
Available language versions: en pl
Issue: Postepy Hig Med Dosw 2017; 71 : 860-866

 

Abstract

Mammals milk, in addition to nutrients, contains many biologically active substances including immunoglobulins, growth factors, cytokines, acute phase proteins, and antimicrobial and antiviral proteins. Thanks to its unique composition, for hundreds of years it is used in post-natal care, treatment of wounds, as well as to fight bacterial and viral infections. The discovery of stem cells and HAMLET complex in breast milk resulted in increased interest in human breast milk as a natural medicine. Milk therapy is devoid of side effects, and breast milk banks may serve as a potential source of milk as a drug substance. In this study we collected information about the possible non-nutritional use of breast milk.

References

  • 1. Aghamohammadi A., Zafari M., Moslemi L.: Comparing the effect of topical application of human milk and dry cord care on umbilical cord separation time in healthy newborn infants. Iran. J. Pediatr., 2012; 22: 158-162
    Google Scholar
  • 2. Ahmadpour-Kacho M., Zahedpasha Y., Hajian K., Javadi G., Talebian H.: The effect of topical application of human milk, ethyl alcohol 96%, and silver sulfadiazine on umbilical cord separation time in newborn infants. Arch. Iran. Med., 2006; 9: 33-38
    Google Scholar
  • 3. Arroyo R., Martín V., Maldonado A., Jiménez E., Fernández L., Rodríguez J.M.: Treatment of infectious mastitis during lactation: antibiotics versus oral administration of Lactobacilli isolated from breast milk. Clin. Infect. Dis., 2010; 50: 1551-1558
    Google Scholar
  • 4. Artym J., Zimecki M.: Milk-derived proteins and peptides in clinical trials. Postępy Hig. Med. Dośw., 2013; 67: 800-816
    Google Scholar
  • 5. Bernatowicz-Łojko U.: Rola pokarmu kobiecego w profilaktyce i leczeniu. Postępy Neonatologii, 2008; 2: 142-143
    Google Scholar
  • 6. Bode L., McGuire M., Rodriguez J.M., Geddes D.T., Hassiotou F., Hartmann P.E., McGuire M.K.: It’s alive: microbes and cells in human milk and their potential benefits to mother and infant. Adv. Nutr., 2014; 5: 571-573
    Google Scholar
  • 7. Chan G.M., Lee M.L., Rechtman D.J.: Effects of a human milk-derived human milk fortifier on the antibacterial actions of human milk. Breastfeed Med., 2007; 2: 205-208
    Google Scholar
  • 8. Farahani L.A., Ghobadzadeh M., Yousefi P.: Comparison of the effect of human milk and topical hydrocortisone 1% on diaper dermatitis. Pediatr. Dermatol., 2013; 30: 725-729
    Google Scholar
  • 9. Fischer W., Gustafsson L., Mossberg A.K., Gronli J., Mork S., Bjerkvig R., Svanborg C.: Human α-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival. Cancer Res., 2004; 64: 2105-2112
    Google Scholar
  • 10. Ghaemi S., Navaei P., Rahimirad S., Behjati M., Kelishadi R.: Evaluation of preventive effects of colostrum against neonatal conjunctivitis: a randomized clinical trial. J. Educ. Health Promot., 2014; 3: 63
    Google Scholar
  • 11. Gotlib J., Belowska J., Panczyk M., Dykowska G., Wójcik G.: Evidence-based Medicine i Evidence-based Nursing Practice – przegląd polskiego piśmiennictwa naukowego. Problemy Pielęgniarstwa, 2014; 22: 223-227
    Google Scholar
  • 12. Gustafsson L., Leijonhufvud I., Aronsson A., Mossberg A.K., Svanborg C.: Treatment of skin papillomas with topical α-lactalbuminoleic acid. N. Engl. J. Med., 2004; 350: 2663-2672
    Google Scholar
  • 13. Hassiotou F., Beltran A., Chetwynd E., Stuebe A.M., Twigger A.J., Metzger P., Trengove N., Lai C.T., Filgueira L., Blancafort P., Hartmann P.E.: Breastmilk is a novel source of stem cells with multilineage differentiation potential. Stem Cells, 2012; 30: 2164-2174
    Google Scholar
  • 14. Hurley W.L., Theil P.K: Perspectives on immunoglobulins in colostrum and milk. Nutrients, 2011; 3: 442-474
    Google Scholar
  • 15. Ibhanesebhor S.E., Otobo E.S.: In vitro activity of human milk against the causative organisms of ophthalmia neonatorum in Benin City, Nigeria. J. Trop. Pediatr., 1996; 42: 327-329
    Google Scholar
  • 16. Jiménez E., Fernández L., Maldonado A., Martín R., Olivares M., Xaus J., Rodríguez J.M.: Oral administration of Lactobacillus strains isolated from breast milk as an alternative for the treatment of infectious mastitis during lactation. Appl. Environ. Microbiol., 2008; 74: 4650-4655
    Google Scholar
  • 17. Kasrae H., Amiri Farahani L., Yousefi P.: Efficacy of topical application of human breast milk on atopic eczema healing among infants: a randomized clinical trial. Int. J. Dermatol., 2015; 54: 966-971
    Google Scholar
  • 18. Knyazeva E.L., Grishchenko V.M., Fadeev R.S., Akatov V.S., Permyakov S.E., Permyakov E.A.: Who is Mr. HAMLET? Interaction of human α-lactalbumin with monomeric oleic acid. Biochemistry, 2008; 47: 13127-13137
    Google Scholar
  • 19. Krauze A., Peradzyńska J., Lange J., Krenke K., Kulus M.: Czy to nadal alergia pokarmowa? Częstość występowania alergii na biał- ko mleka krowiego u dzieci w 2 roku życia z atopowym zapaleniem skóry. Współczesna Alergologia Info., 2009; 4: 178-183
    Google Scholar
  • 20. Lara-Villoslada F., Olivares M., Sierra S., Rodríguez J.M., Boza J., Xaus J.: Beneficial effects of probiotic bacteria isolated from breast milk. Br. J. Nutr., 2007; 98: S96-S100
    Google Scholar
  • 21. Lis J., Orczyk-Pawiłowicz M., Kątnik-Prastowska I.: Białka mlekaludzkiego zaangażowane w procesy immunologiczne. Postępy Hig. Med. Dośw., 2013; 67: 529-547
    Google Scholar
  • 22. Lönnerdal B.: Bioactive proteins in breast milk. J. Paediatr. Child Health, 2013; 49: 1-7
    Google Scholar
  • 23. Mohammadzadeh A., Farhat A., Esmaeily H.: The effect of breast milk and lanolin on sore nipples. Saudi. Med. J., 2005; 26: 1231-1234
    Google Scholar
  • 24. Mossberg A.K., Hou Y., Svensson M., Holmqvist B., Svanborg C.: HAMLET treatment delays bladder cancer development. J. Urol., 2010; 183: 1590-1597
    Google Scholar
  • 25. Nehring-Gugulska M., Żukowska-Rubik M., Pietkiewicz A.P.: Karmienie piersią w teorii i praktyce. Podręcznik dla doradców i konsultantów laktacyjnych oraz położnych, pielęgniarek i lekarzy. Medycyna Praktyczna; Kraków 2012
    Google Scholar
  • 26. Permyakov S.E., Knyazeva E.L., Khasanova L.M., Fadeev R.S.,Zhadan A.P., Roche-Hakansson H., Håkansson A.P., Akatov V.S., Permyakov E.A.: Oleic acid is a key cytotoxic component of HAMLET-like complexes. Biol. Chem., 2012; 393: 85-92
    Google Scholar
  • 27. Rak K.A., Bronkowska M.: Immunologiczne znaczenie siary. Hygeia Public Health, 2014; 49: 249-254
    Google Scholar
  • 28. World Health Organization: Care of the Umbilical Cord: A Review of the Evidence: Division of Reproductive Health (Technical Support), Family and Reproductive Health, World Health Organization; 1998
    Google Scholar
  • 29. Zar H.J.: Neonatal Chlamydial infections: prevention and treatment. Pediatr. Drugs, 2005; 7: 103-110
    Google Scholar

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