COMMENTARY ON THE LAW

Phosphodiesterases of cyclic GMP

Hanna Wróblewska , Wojciech Gorczyca

Published: 2001-09-15

GICID: 01.3001.0000.3463

Available language versions: en

Issue: Postepy Hig Med Dosw 2001; 55 (5)

Abstract

Phosphodiesterases of cyclic nucleotides (PDEs) are enzymes hydrolyzing cGMP, cAMP or both and are regulated in several different ways. In this paper we summarize current data on structure, cellular and tissue localization, regulation and function of different PDE families that hydrolyze cGMP