T Robak 1
1. Zakład Farmakologii Klinicznej AM, Lodzi.
Published:
GICID: 01.3001.0000.2891
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1992; 46 (1)
Abstract
The new aspects in the pathogenesis of aplastic anaemia and others acquired states of bone marrow aplasia as well as congenital defects of the marrow stem cells have been reviewed. Role of immune mechanisms, viruses, chemical and irradiation exposure in the etiology and pathophysiology of bone marrow failure is presented. The new achievements in the treatment of aplastic anaemias including bone marrow transplantation, antilymphocyte globulin, cyclosporin A, high doses of 6-methyl prednisolone and recombinant haemopoietic growth factors are also discussed.