[Role of adhesion molecules in interactions of endothelium with leukocytes in inflammatory processes]

D Zapolska-Downar 1 , A Zapolski-Downar

1. Zakład Biochemii Klinicznej i Diagnostyki Laboratoryjnej Pomorskiej AkademiiMedycznej, Szczecinie.

Published:

GICID: 01.3001.0000.2845

Available language versions: en pl

Issue: Postepy Hig Med Dosw 1994; 48 (3)

Abstract

This paper reviews recent work regarding the molecules that mediate leukocyte-endothelial cell adhesion, describes the underlying principles of leukocyte migration, and discusses a model of the sequence of events that allows a leukocyte to attach to endothelium and migrate into tissue. Pathophysiological importance of the adhesion molecules in the development of different states of inflammation has been also presented.

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