F Kacprzyk 1
1. Klinika Nefrologiczna Instytutu Medycyny Wewnetrznej Akademii Medycznej w Lodzi.
Published:
GICID: 01.3001.0000.3049
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1995; 49 (4)
Abstract
IL-6 synthesized by various types of cells and has multiple biological functions. In the kidney, IL-6 is synthesized by mesangial cells and acts as an autocrine growth factor. IL-6 was demonstrated in the glomerular mesangium and in the urine of patients with proliferative glomerulonephritis, suggesting that it has an important role in the pathogenesis of renal glomerular diseases.