[The role of endothelin in regulation of vascular tone in physiology and pathology]

J Jośko ¹ , B Gwóźdź , S Hendryk

1. Katedra i Zakład Fizjologii Slaskiej Akademii Medycznej w Zabrzu.

Published:

GICID: 01.3001.0000.3143

Available language versions: en pl

Issue: Postepy Hig Med Dosw 1997; 51 (4)

Abstract

This paper discuss importance of the endothelin, present in the plasma and other fluids, on the vascular smooth muscles in physiology and pathology. Endothelin-1 as one of the very strong vasoconstructive peptides influences the vascular tone. We discuss the competitive action of vasoconstrictors and vasodilators in promoting of vasospasm, especially in the states, where endothelial cells are injured.