M Kobzdej 1 , L Strzadała
1. Laboratorium Immunologii Komórkowej Instytutu Immunologii i Terapii Doświadczalnejim. L. Hirszfelda PAN we Wrocławiu.
Published:
GICID: 01.3001.0000.3074
Available language versions: en pl
Issue: Postepy Hig Med Dosw 1996; 50 (2)
Abstract
This article describes the significance of the mouse transgenic model in elucidation of the role and the oncogenic potential of such genes as N-ras, pim-1, bcl-2, myc and p53. The role of gene targetting by homologous recombination in the study of preneoplastic state in the mice model was also discussed.