Treatment of Helicobacter pylori infections in the light of the increase of antibiotic resistance

REVIEW ARTICLE

Treatment of Helicobacter pylori infections in the light of the increase of antibiotic resistance

Eliza Mnich 1 , Jakub Ibran 1 , Magdalena Chmiela 1

1. Katedra Immunologii i Biologii Infekcyjnej, Instytut Mikrobiologii, Biotechnologii i Immunologii, Wydział Biologii i Ochrony Środowiska, Uniwersytet Łódzki,

Published: 2018-03-19
DOI: 10.5604/01.3001.0011.6469
GICID: 01.3001.0011.6469
Available language versions: en pl
Issue: Postepy Hig Med Dosw 2018; 72 : 143-158

 

Abstract

The aim of this study was to present the risks associated with the occurrence of Helicobacter pylori (H. pylori) infection in humans and the problems related to eradication procedures with the use of antibiotic treatment. The content provides an overview of the available methods of infection diagnosis and recommended therapeutic schemes as well as potential alternative schedules of treatment. Mechanisms of H. pylori resistance to commonly used antibiotics including the mutations in the genome leading to resistance and the incidence of resistant strains in the world has been described. Finally, we introduced substances with some potential in eradication therapy, including probiotics, plant formulations as well as polyunsaturated fatty acids and ascorbic acid.

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