Ewa Kostarczyk
Opublikowany: 2000-07-15
GICID: 01.3001.0000.3289
Dostępne wersje językowe: en
Wydanie: Postepy Hig Med Dosw 2000; 54 (4)
Abstrakt
Review of the interacting elements of nociceptive, neuroimmune and neuroendocrine systems with a stress on sympathetic innervation of the lymphoid organs. Special attention is given to dysfunctions within the nociceptive, neuroendocrine and immune systems due to: damage to the:1) afferent fibers; 2) sympatho-adrenal system; 3) structures of the hypothalamo-pituitary-adrenal axis. The role of peripheral immunocytes in the generation of pain, including local cytokines, opioids and CRF is also discussed.