Guzy jajnika: Częstość występowania, typ histologiczny i leczenie zmian w grupie pediatrycznej

ORYGINALNY ARTYKUŁ

Guzy jajnika: Częstość występowania, typ histologiczny i leczenie zmian w grupie pediatrycznej

Patrycja Sosnowska-Sienkiewicz 1 , Piotr Nogal 2 , Dawid Gawron 2 , Korneliusz Wójcik 2 , Danuta Januszkiewicz-Lewandowska 3 , Przemysław Mańkowski 1

1. Department of Pediatric Surgery, Traumatology and Urology, Poznan University of Medical Sciences, Poland
2. Student Research Group: Pediatric Surgery, Department of Pediatric Surgery, Traumatology and Urology, Poznan University of Medical Sciences, Poland
3. Department of Pediatric Oncology, Haematology and Transplantology, Poznan University of Medical Sciences, Poland

Opublikowany: 2021-04-29
DOI: 10.5604/01.3001.0014.8603
GICID: 01.3001.0014.8603
Dostępne wersje językowe: pl en
Wydanie: Postepy Hig Med Dosw 2021; 75 : 292-296

 

Abstrakt

Background: The aim of this study was to evaluate the incidence and histological type of lesions affecting the ovaries and to analyze employed methods of invasive treatment. Materials&Methods: Medical records of patients who were treated surgically for ovarian tumors in the years 2015 -2019 were reviewed. The study group was comprised of 31 female patients. Results: During 5 years time, there were 31 girls in the age from 3 months to 17 years hospitalized in the department. The mean age was 11 years. Histopathological examination was performed in all of these cases. 12 patients were diagnosed with malignant lesion, 19 with benign lesion. The most commonly diagnosed malignant tumors were a dysgerminoma and a mixed germ cell tumor. In the group of benign lesions, the most frequent tumor type was mature teratoma. The first occurring symptom was abdominal pain. Some of the lesions were diagnosed accidentally during ultrasonography. The diagnostics was expanded depending on the size of the tumor, staging and clinical condition of the patient. All the patients were treated surgically, 16 of them underwent laparoscopic surgery. Torsion of the ovary or oviduct was observed in 3 cases. Chemotherapy was introduced in 8 cases as complementary treatment. Conclusions: The most commonly diagnosed tumor was mature teratoma. Ultrasonography is the most frequent method of the ovaries’ examination. Ovarian lesions are characterized by non-specific clinical symptoms, which is associated with prevalent incidental detection during ultrasonography.

Przypisy

  • 1. Al Jama F.E., Al Ghamdi A.A., Gasim T., Al Dakhiel S.A., Rahman J.,Rahman M.S.: Ovarian tumors in children and adolescents – a clinicalstudy of 52 patients in a university hospital. J. Pediatr. Adolesc.Gynecol., 2011; 24: 25–28
    Google Scholar
  • 2. Amies Oelschlager A., Gow K.W., Morse C.B., Lara-Torre E.: Managementof large ovarian neoplasms in pediatric and adolescentfemales. J. Pediatr. Adolesc. Gynecol., 2016; 29: 88–94
    Google Scholar
  • 3. Brookfield K.F., Cheung M.C., Koniaris L.G., Sola J.E., Fischer A.C.:A population-based analysis of 1037 malignant ovarian tumors inthe pediatric population. J. Surg. Res., 2009; 156: 45–49
    Google Scholar
  • 4. Brown M.F., Hebra A., McGeehin K., Ross A.J.3rd: Ovarian massesin children: A review of 91 cases of malignant and benign masses. J.Pediatr. Surg., 1993; 28: 930–933
    Google Scholar
  • 5. Cecchetto G.: Gonadal germ cell tumors in children and adolescents.J. Indian Assoc. Pediatr. Surg., 2014; 19: 189–194
    Google Scholar
  • 6. Chybicka A., Sawicz-Birkowska K., Adamkiewicz-Drożyńska E.M.:Onkologia i hematologia dziecięca. Guzy germinalne. WydawnictwoLekarskie PZWL, Warszawa 2008
    Google Scholar
  • 7. Cribb B., Vishwanath N., Upadhyay V.: Paediatric ovarian lesions– the experience at Starship Children’s Hospital, New Zealand. N. Z.Med. J., 2014; 127: 41–51
    Google Scholar
  • 8. Djukic M., Stankovic Z., Vasiljevic M., Savic D., Lukac B., DjuricicS.: Laparoscopic management of ovarian benign masses. Clin. Exp.Obstet. Gynecol., 2014; 41: 296–299
    Google Scholar
  • 9. Kunpalin Y., Triratanachat S., Tantbirojn P.: Proportion of ovariancancers in overall ovarian masses in Thailand. Asian Pac. J. CancerPrev., 2014; 15: 7929–7934
    Google Scholar
  • 10. Matsushita H., Watanabe K., Yokoi T., Wakatsuki A.: Unexpectedovarian malignancy following laparoscopic excision of adnexalmasses. Hum. Reprod., 2014; 29: 1912–1917
    Google Scholar
  • 11. Menczer J., Sadetzki S., Murad H., Barda G., Andreev H., BarchanaM.: Childhood and adolescent ovarian malignant tumors in Israel.A nationwide study. Acta Obstet. Gynecol. Scand., 1999; 78: 813–817
    Google Scholar
  • 12. Oue T., Uehara S., Sasaki T., Nose S., Saka R., Yamanaka H., UenoT., Tazuke Y., Okuyama H.: Treatment and ovarian preservation inchildren with ovarian tumors. J. Pediatr. Surg., 2015; 50: 2116–2118
    Google Scholar
  • 13. Özcan R., Kuruoğlu S., Dervişoğlu S., Eliçevik M., Emir H.,Büyükünal C.: Ovary-sparing surgery for teratomas in children.Pediatr. Surg. Int., 2013; 29: 233–237
    Google Scholar
  • 14. Rogers E.M., Casadiego Cubides G., Lacy J., Gerstle J.T., Kives S.,Allen L.: Preoperative risk stratification of adnexal masses: Can we predict the optimal surgical management? J. Pediatr. Adolesc. Gynecol.,2014; 27: 125–128
    Google Scholar
  • 15. Spinelli C., Pucci V., Strambi S., Piccolo R.L., Martin A., MessineoA.: Treatment of ovarian lesions in children and adolescents:A retrospective study of 130 cases. Pediatr. Hematol. Oncol., 2015;32: 199–206
    Google Scholar
  • 16. Taskinen S., Fagerholm R., Lohi J., Taskinen M.: Pediatric ovarianneoplastic tumors: Incidence, age at presentation, tumor markersand outcome. Acta Obstet. Gynecol. Scand., 2015; 94: 425–429
    Google Scholar
  • 17. Terenziani M., Spinelli M., Jankovic M., Bardi E., Hjorth L., HauptR., Michel G., Byrne J.: Practices of pediatric oncology and hematologyproviders regarding fertility issues: A European survey. Pediatr.Blood Cancer, 2014; 61: 2054–2058
    Google Scholar
  • 18. Von Allmen D.: Malignant lesions of the ovary in childhood.Semin. Pediatr. Surg., 2005; 14: 100–105
    Google Scholar
  • 19. Walczewska M., Mocarska A., Burdan F., Janczarek M.,Żelazowska-Cieślińska I., Starosławska E.: Diagnosis of benign ovarianlesions using imaging techniques. Pol. Merkur. Lek., 2015; 38:55–60
    Google Scholar
  • 20. Yousef Y., Pucci V., Emil S.: The relationship between intra-operativerupture and recurrence of pediatric ovarian neoplasms: Preliminaryobservations. J. Pediatr. Adolesc. Gynecol., 2016; 29: 111–116
    Google Scholar
  • 21. Zhang M., Jiang W., Li G., Xu C.: Ovarian masses in children andadolescents – an analysis of 521 clinical cases. J. Pediatr. Adolesc.Gynecol., 2014; 27: e73–e77
    Google Scholar

Pełna treść artykułu

Przejdź do treści