A role of protein kinase C isoforms in tumorigenicity and apoptotic cells death A role of protein kinase C isoforms in tumorigenicity and apoptotic cells death

Maria Rybczyńska Krzysztof Książek Jolanta Kaczmarek 1

1. Uniwersytet im. Adama Mickiewicza w Poznaniu

Opublikowany: 2000-11-15

GICID: 01.3001.0000.3309

Dostępne wersje językowe: en

Wydanie: Postepy Hig Med Dosw 2000; 54 (6)

Abstrakt

Protein kinase C comprises a family of at least 13 distinct serine/threonine kinase isoenzymes that have important action in transmembrane signal transduction pathways and have been reported to regulate cell proliferation, differentiation, cell-to-cell interaction, cytoskeletal functions, gene transcription, apoptosis and drug resistance. The results of investigations show differential redistribution isozymes in each organs and their specyfic activity in determined diseases.

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