Biomechanic shear stress in carotid arteries and atherosclerosis development

Radosław Kaźmierski

Opublikowany: 2003-11-15

GICID: 01.3001.0000.3566

Dostępne wersje językowe: en

Wydanie: Postepy Hig Med Dosw 2003; 57 (6)

Abstrakt

One of the major hemodynamic forces acting on blood vessels is shear stress, which is, the friction force between the endothelial cell surface and flowing blood. Arterial shear stress within physiologic range (15-70 dyne/cm2) induces endothelial quiescence and an atheroprotective gene expression profile. Low shear stress ( 70 dyne/cm2) induce prothrombotic state.

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