GLOSA LUB KOMENTARZ PRAWNICZY
Leczenie układowych zapaleń naczyń z przeciwciałami ANCA i zajęciem nerek
Olumide Olatubosun Rowaiye 1 , Mariusz Kusztal 1 , Wacław Weyde 2 , Marian Klinger 11. Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland
2. Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland; Faculty of Dentistry, Wroclaw Medical University, Wroclaw, Poland; Fresenius Polska
Opublikowany: 2016-06-28
DOI: 10.5604/17322693.1207508
GICID: 01.3001.0009.6845
Dostępne wersje językowe: pl en
Wydanie: Postepy Hig Med Dosw 2016; 70 : 654-667
Abstrakt
Przypisy
- 1. Alberici F., Jayne D.R.: Impact of rituximab trials on the treatmentof ANCA-associated vasculitis. Nephrol. Dial. Transplant., 2014; 29:1151-1159
Google Scholar - 2. Basu N., McClean A., Harper L., Amft E.N., Dhaun N., Luqmani R.A.,Little M.A., Jayne D.R., Flossmann O., McLaren J., Kumar V., Erwig L.P.,Reid D.M., Jones G.T., Macfarlane G.J.: Explaining fatigue in ANCA-associatedvasculitis. Rheumatology, 2013; 52: 1680-1685
Google Scholar - 3. Basu N., McClean A., Harper L., Amft E.N., Dhaun N., Luqmani R.A.,Little M.A., Jayne D.R., Flossmann O., McLaren J., Kumar V., Erwig L.P.,Reid D.M., Macfarlane G.J.: Jones G.T.: The characterisation and determinantsof quality of life in ANCA associated vasculitis. Ann. Rheum.Dis., 2014; 73: 207-211
Google Scholar - 4. Beck L., Bomback A.S., Choi M.J., Holzman L.B., Langford C., MarianiL.H., Somers M.J., Trachtman H., Waldman M.: KDOQI US commentaryon the 2012 KDIGO clinical practice guideline for glomerulonephritis.Am. J. Kidney Dis., 2013; 62: 403-441
Google Scholar - 5. Berden A.E., Ferrario F., Hagen E.C., Jayne D.R., Jennette J.C., Joh K.,Neumann I., Noël L.H., Pusey C.D., Waldherr R., Bruijn J.A., Bajema I.M.:Histopathologic classification of ANCA-associated glomerulonephritis.J. Am. Soc. Nephrol., 2010; 21: 1628-1636
Google Scholar - 6. Berden A., Göçeroglu A., Jayne D., Luqmani R., Rasmussen N., BruijnJ.A., Bajema I. Diagnosis and management of ANCA associated vasculitis.BMJ, 2012; 344: e26
Google Scholar - 7. Birck R., Warnatz K., Lorenz H.M., Choi M., Haubitz M., Grünke M.,Peter H.H., Kalden J.R., Göbel U., Drexler J.M., Hotta O., Nowack R., VanDer Woude F.J.: 15-Deoxyspergualin in patients with refractory ANCA–associated systemic vasculitis: a six-month open-label trial to evaluatesafety and efficacy. J. Am. Soc. Nephrol., 2003; 14: 440-447
Google Scholar - 8. Bomback A.S., Appel G.B., Radhakrishnan J., Shirazian S., Herlitz L.C.,Stokes B., D’Agati V.D., Markowitz G.S.: ANCA-associated glomerulonephritisin the very elderly. Kidney Int., 2011; 79: 757-764
Google Scholar - 9. Bontscho J., Schreiber A., Manz R.A., Schneider W., Luft F.C., KettritzR.: Myeloperoxidase-specific plasma cell depletion by bortezomib protectsfrom antineutrophil cytoplasmic autoantibodies-induced glomerulonephritis.J. Am. Soc. Nephrol., 2011; 22: 336-348
Google Scholar - 10. Brix S.R., Krebs C., Noriega M., Janneck M., Iking-Konert C., WiechT., Panzer U., Stahl R.A.: CCL 18 in relapsing ANCA-associated necrotizingglomerulonephritis. Nephron, 2015; 129: 112-113 (17th InternationalVasculitis & ANCA Workshop)
Google Scholar - 11. Buhaescu I., Yood R.A., Izzedine H.: Serum procalcitonin in systemicautoimmune diseases – where are we now? Semin. ArthritisRheum., 2010; 40: 176-183
Google Scholar - 12. Bunch D.O., Mendoza C.E., Aybar.L.T., Kotzen E.S., Colby K.R., Hu Y.,Hogan.SL., Poulton C.J., Schmitz J.L., Falk R.J., Nachman P.H., PendergraftW.F., McGregor J.G.: Gleaning relapse risk from B cell phenotype:decreased CD5+ B cells portend a shorter time to relapse after B celldepletion in patients with ANCA-associated vasculitis. Ann. Rheum.Dis., 2015; 74: 1784-1786
Google Scholar - 13. Calich A.L., Puéchal X., Pugnet G., London J., Terrier B., CharlesP., Mouthon L., Guillevin L.: Rituximab for induction and maintenancetherapy in granulomatosis with polyangiitis (Wegener’s). Resultsof a single-center cohort study on 66 patients. J. Autoimmun., 2014;50: 135-141
Google Scholar - 14. Carpenter D.M., Kadis J.A., Devellis R.F., Hogan S.L., Jordan J.M.: Theeffect of medication-related support on the quality of life of patientswith vasculitis in relapse and remission. J. Rheumatol., 2011; 38: 709-715
Google Scholar - 15. Carson K.R., Evens A.M., Richey E.A., Habermann T.M., Focosi D.,SeymourJ.F., Laubach J., Bawn S.D., Gordon L.I., Winter J.N., FurmanR.R., VoseJ.M., Zelenetz A.D., Mamtani R., Raisch D.W., et al.: Progressivemultifocal leukoencephalopathy after rituximab therapy in HIV-negativepatients: a report of 57 cases from the Research on Adverse DrugEvents and Reports project. Blood, 2009;113: 4834-4840
Google Scholar - 16. Cartin-Ceba R., Golbin J.M., Keogh K.A., Peikert T., Sánchez-MenéndezM., Ytterberg S.R., Fervenza F.C., Specks U.: Rituximab for remissioninduction and maintenance in refractory granulomatosis with polyangiitis(Wegener’s): ten-year experience at a single center. ArthritisRheum., 2012; 64: 3770-3778
Google Scholar - 17. CCX168 Phase II Data in ANCA-Associated Renal Vasculitis. http://ir.chemocentryx.com/releasedetail.cfm?ReleaseID=811237 (28.02.2016)
Google Scholar - 18. de Groot K., Harper L., Jayne D.R., Flores Suarez L.F., Gregorini G.,Gross W.L., Luqmani R., Pusey C.D., Rasmussen N., Sinico R.A., Tesar V.,Vanhille P., Westman K., Savage C.O.: Pulse versus daily oral cyclophosphamidefor induction of remission in antineutrophil cytoplasmicantibody-associated vasculitis: a randomized trial. Ann. Intern. Med.,2009; 150: 670-680
Google Scholar - 19. de Groot K., Rasmussen N., Bacon P.A., Tervaert J.W., Feighery C.,Gregorini G., Gross W.L., Luqmani R., Jayne D.R.: Randomized trial ofcyclophosphamide versus methotrexate for induction of remission inearly systemic antineutrophil cytoplasmic antibody-associated vasculitis.Arthritis Rheum., 2005; 52: 2461-2469
Google Scholar - 20. de Joode A.A., Sanders J.S., Smid W.M., Stegeman C.A.: Plasmapheresisrescue therapy in progressive systemic ANCA-associated vasculitis:single-center results of stepwise escalation of immunosuppression.J. Clin. Apher., 2014; 29: 266-272
Google Scholar - 21. Draibe J., Poveda R., Fulladosa X., Vidaller A., Zulberti C., Goma M.,Pujol R., Ripoll E., Torras J., Grinyó J.M.: Use of mycophenolate in ANCA-associatedrenal vasculitis: 13 years of experience at a universityhospital. Nephrol. Dial.Transplant., 2015; 30: 132-137
Google Scholar - 22. Eisenberger U., Fakhouri F., Vanhille P., Beaufils H., Mahr A., GuillevinL., Lesavre P., Noël L.H.: ANCA-negative pauci-immune renalvasculitis: histology and outcome. Nephrol. Dial. Transplant., 2005;20: 1392-1399
Google Scholar - 23. European Vasculitis Study Group. Clinical Trial Protocol: REMAIN.http://www.vasculitis.org/images/documents/remain%20jan%202006.pdf (28.02.2016)
Google Scholar - 24. Falk R.J.: Identification and management of relapsing disease ingranulomatosis with polyangiitis and microscopic polyangiitis. In:UpToDate, eds.: R.J. Glassock, G.B. Appel. UpToDate, Waltham, Massachusetts
Google Scholar - 25. Falk R.J.: Maintenance immunosuppressive therapy in granulomatosiswith polyangiitis and microscopic polyangiitis. In: UpToDate,eds.: G.B. Appel, F.C.Fervenza. UpToDate, Waltham, Massachusetts
Google Scholar - 26. Falk R.J.: Prognosis in granulomatosis with polyangiitis and microscopicpolyangiitis,and management of those who develop end-stagerenal disease. In: UpToDate, eds.: G.B. Appel, F.C. Fervenza. UpToDate,Waltham, Massachusetts
Google Scholar - 27. Flossmann O., Baslund B., Bruchfeld A., Tervaert J.W., Hall C., HeinzelP., Hellmich B., Luqmani R.A., Nemoto K., Tesar V., Jayne D.R.: Deoxyspergualin in relapsing and refractory Wegener’s granulomatosis.Ann. Rheum. Dis., 2009; 68: 1125-1130
Google Scholar - 28. Flossmann O., Berden A., de Groot K., Hagen C., Harper L., HeijlC., Höglund P., Jayne D., Luqmani R., Mahr A., Mukhtyar C., Pusey C.,Rasmussen N., Stegeman C., Walsh M., et al.: Long-term patient survivalin ANCA-associated vasculitis. Ann. Rheum. Dis. 2011; 70: 488-494
Google Scholar - 29. Furuta S., Jayne D.R.: Antineutrophil cytoplasm antibody-associatedvasculitis: recent developments. Kidney Int., 2013; 84: 244-249
Google Scholar - 30. Galesic K., Ljubanovic D., Horvatic I.: Treatment of renal manifestationsof ANCA-associated vasculitis. J. Nephropathol., 2013; 2: 6-19
Google Scholar - 31. Geetha D., Specks U., Stone J.H., Merkel P.A., Seo P., Spiera R., LangfordC.A., Hoffman G.S., Kallenberg C.G., St Clair E.W., Fessler B.J., DingL., Tchao N.K., Ikle D., et al.. Rituximab versus cyclophosphamide forANCA-associated vasculitis with renal involvement. J. Am. Soc. Nephrol.,2015; 26: 976-985
Google Scholar - 32. Gigante A., Gasperini M.L., Barbano B., Liberatori M., Sardo L., JovanovicT., Giannakakis K., Cianci R., Amoroso A.: Gabexate mesylateas treatment in the course of ANCA-negative microscopic polyangiitis.Ren. Fail., 2013; 35: 721-724
Google Scholar - 33. Gregersen J.W., Kristensen T., Krag S.R., Birn H., Ivarsen P.: Earlyplasma exchange improves outcome in PR3-ANCA-positive renal vasculitis.Clin. Exp. Rheumatol., 2012; 30: S39-S47
Google Scholar - 34. Guerry M.J., Brogan P., Bruce I.N., D’Cruz D.P., Harper L., Luqmani R.,Pusey C.D., Salama A.D., Scott D.G., Savage C.O., Watts R.A., Jayne D.R.:Recommendations for the use of rituximab in anti-neutrophil cytoplasmantibody-associated vasculitis. Rheumatology, 2012; 51: 634-643
Google Scholar - 35. Guillevin L., Pagnoux C., Karras A., Khouatra C, Aumaître O, CohenP, Maurier F, Decaux O., Ninet J., Gobert P., Quémeneur T., Blanchard–Delaunay C., Godmer P., Puéchal X., Carron P.L., et al.: Rituximab versusazathioprine for maintenance in ANCA-associated vasculitis. N. Engl.J. Med., 2014; 371: 1771-1780
Google Scholar - 36. Han F., Liu G., Zhang X, Li X., He Q., He X., Li Q., Wang S., Wang H.,Chen J.: Effects of mycophenolate mofetil combined with corticosteroidsfor induction therapy of microscopic polyangiitis. Am. J. Nephrol.,2011; 33: 185-192
Google Scholar - 37. Harper L., Morgan M.D., Walsh M., Hoglund P., Westman K., FlossmannO., Tesar V., Vanhille P., de Groot K., Luqmani R., Flores-SuarezL.F., Watts R., Pusey C., Bruchfeld A., Rasmussen N., et al.: Pulse versusdaily oral cyclophosphamide for induction of remission in ANCA–associated vasculitis: long-term follow-up. Ann. Rheum. Dis., 2012;71: 955-960
Google Scholar - 38. Harper L., Savage C.O.: ANCA-associated renal vasculitis at the endof the twentieth century – a disease of older patients. Rheumatology,2005; 44: 495-501
Google Scholar - 39. Hasegawa M., Hattori K., Sugiyama S., Asada H., Yamashita H.,Takahashi K., Hayashi H., Koide S., Sato W., Yuzawa Y.: A retrospectivestudy on the outcomes of MPO-ANCA-associated vasculitis in dialysis–dependent patients. Mod. Rheumatol., 2016; 26: 110-114
Google Scholar - 40. Hiemstra T.F., Walsh M., Mahr A., Savage C.O., de Groot K., HarperL., Hauser T., Neumann I., Tesar V., Wissing K.M., Pagnoux C., SchmittW., Jayne D.R.: Mycophenolate mofetil vs azathioprine for remissionmaintenance in antineutrophil cytoplasmic antibody-associated vasculitis:a randomized controlled trial. JAMA, 2010; 304: 2381-2388
Google Scholar - 41. Hogan P.C., O’Connell R.M., Scollard S., Browne E., Hackett E.E.,Feighery C.: Biomarkers predict relapse in granulomatosis with polyangiitis.J. Biomark., 2014; 2014: 596503
Google Scholar - 42. Hu W., Liu C., Xie H., Chen H., Liu Z., Li L.: Mycophenolate mofetilversus cyclophosphamide for inducing remission of ANCA vasculitiswith moderate renal involvement. Nephrol. Dial. Transplant., 2008;23: 1307-1312
Google Scholar - 43. Jayne D.: Newer and future treatment of vasculitis. In: Textbookof systemic vasculitis, ed.: A. Sharma. Jaypee Brothers Medical Publishers,New Delhi 2015, 238-244
Google Scholar - 44. Jayne D.R, Chapel H., Adu D., Misbah S., O’Donoghue D., Scott D.,Lockwood C.M.: Intravenous immunoglobulin for ANCA-associated systemicvasculitis with persistent disease activity. QJM, 2000; 93: 433-439
Google Scholar - 45. Jayne D.R., Gaskin G., Rasmussen N., Abramowicz D., Ferrario F.,Guillevin L., Mirapeix E., Savage C.O., Sinico R.A., Stegeman C.A., WestmanK.W., van der Woude F.J., de Lind van Wijngaarden R.A., Pusey C.D.:Randomized trial of plasma exchange or high-dosage methylprednisoloneas adjunctive therapy for severe renal vasculitis. J. Am. Soc.Nephrol., 2007; 18: 2180-2188
Google Scholar - 46. Jayne D., Rasmussen N., Andrassy K., Bacon P., Tervaert J.W., DadonienéJ., Ekstrand A., Gaskin G., Gregorini G., de Groot K., Gross W.,Hagen E.C., Mirapeix E., Pettersson E., Siegert C., et al.: A randomizedtrial of maintenance therapy for vasculitis associated with antineutrophilcytoplasmic autoantibodies. N. Engl. J. Med., 2003; 349: 36-44
Google Scholar - 47. Jennette J.C., Falk R.J.: New insight into the pathogenesis of vasculitisassociated with antineutrophil cytoplasmic autoantibodies. Curr.Opin. Rheumatol., 2008; 20: 55-60
Google Scholar - 48. Jha V.: Renal and systemic vasculitis. In: Comprehensive ClinicalNephrology, eds.: J. Floege, R.J. Johnson, J. Feehally. Saunders, St. Louis,Missouri, 2010, 292-307
Google Scholar - 49. Jones R., Harper L., BallarinJ., Blockmans D., Brogan P., BruchfeldA., Cid A., Dahlsveen K.,Dezoysa J., Lanyon P., Peh C.A., Tesar V., VaglioA., Walsh M., Walsh D., et al.: A randomized trial of mycophenolatemofetil versus cyclophosphamide for remission induction of ANCA–associated vasculitis: “MYCYC”. On behalf of the European vasculitisstudy group [abstract]. Presse Med., 2013; 42: 678-679
Google Scholar - 50. Jones R.B., Furuta S., Tervaert J.W., Hauser T., Luqmani R., MorganM.D., Peh C.A., Savage C.O., Segelmark M., Tesar V., van Paassen P.,Walsh M., Westman K., Jayne D.R.: Rituximab versus cyclophosphamidein ANCA-associated renal vasculitis: 2-year results of a randomisedtrial. Ann. Rheum. Dis., 2015; 74: 1178-1182
Google Scholar - 51. Jones R.B., Tervaert J.W., Hauser T., Luqmani R., Morgan M.D., PehC.A., Savage C.O., Segelmark M., Tesar V., van Paassen P., Walsh D., WalshM., Westman K., Jayne D.R.: Rituximab versus cyclophosphamide inANCA-associated renal vasculitis. N. Engl. J. Med., 2010; 363: 211-220
Google Scholar - 52. Joy M.S., Hogan S.L., Jennette J.C., Falk R.J., Nachman P.H.: A pilotstudy using mycophenolate mofetil in relapsing or resistant ANCAsmall vessel vasculitis. Nephrol. Dial. Transplant., 2005; 20: 2725-2732
Google Scholar - 53. Kameoka Y., Kishi F., Yamakawa Y., Nagasawa R., Ikeda S., KouraM., Matsuda J., Nakayama T., Suzuki K.: Synthetic immunoglobulin selectedfrom clone library for MPO-ANCA-related vasculitis. Nephron,2015; 129: 145-146 (17th International Vasculitis & ANCA Workshop)
Google Scholar - 54. Karagas M.R., Cushing G.L. Jr, Greenberg E.R., Mott L.A., SpencerS.K., Nierenberg D.W.: Non-melanoma skin cancers and glucocorticoidtherapy. Br. J. Cancer, 2001; 85: 683-686
Google Scholar - 55. Knight A., Hallenberg H., Baecklund E.: Efficacy and safety of rituximabas maintenance therapy for relapsing granulomatosis withpolyangiitis – a case series. Clin. Rheumatol., 2014; 33: 841-848
Google Scholar - 56. Knoll G., Cockfield S., Blydt-Hansen T., Baran D., Kiberd B., LandsbergD., Rush D., Cole E.: Canadian Society of Transplantation consensusguidelines on eligibility for kidney transplantation. CMAJ, 2005;173: S1-S25
Google Scholar - 57. Komatsuda A., Omokawa A., Fujiwara T., Sato R, Togashi M, OkuyamaS,Sawada K, Wakui H.: Serum procalcitonin levels in patients withmyeloperoxidase-antineutrophil cytoplasmic antibodies-associatedglomerulonephritis. Am. J. Med. Sci., 2012; 343: 136-140
Google Scholar - 58. Kötter I., Daikeler T., Amberger C., Tyndall A., Kanz L.: Autologousstem cell transplantation of treatment-resistant systemic vasculitis – asingle center experience and review of the literature. Clin. Nephrol.,2005; 64: 485-489
Google Scholar - 59. Kusumoto S., Tanaka Y., Ueda R., Mizokami M.: Reactivation ofhepatitis B virus following rituximab-plus-steroid combination chemotherapy.J. Gastroenterol., 2011; 46: 9-16
Google Scholar - 60. Lieberthal J.G., Cuthbertson D., Carette S., Hoffman G.S., KhalidiN.A., Koening C.L., Langford C.A., Maksimowicz-McKinnon K., Seo P.,Specks U., Ytterberg S.R., Merkel P.A., Monach P.A.: Urinary markers inrelapsing antineutrophil cytoplasmic antibody-associated vasculitis.J. Rheumatol., 2013; 40: 674-683
Google Scholar - 61. Lionaki S., Hogan S.L., Jennette C.E., Hu Y., Hamra J.B., JennetteJ.C., Falk R.J., Nachman P.H.: The clinical course of ANCA small-vesselvasculitis on chronic dialysis. Kidney Int., 2009; 76: 644-651
Google Scholar - 62. Little M.A., Pusey C.D.: Glomerulonephritis due to antineutrophilcytoplasm antibody-associated vasculitis: an update on approaches tomanagement. Nephrology, 2005; 10: 368-376
Google Scholar - 63. Lovric S., Erdbruegger U., Kümpers P., Woywodt A., Koenecke C.,Wedemeyer H., Haller H., Haubitz M.: Rituximab as rescue therapy inanti-neutrophil cytoplasmic antibody-associated vasculitis: a single–centre experience with 15 patients. Nephrol. Dial. Transplant., 2009;24: 179-185
Google Scholar - 64. Mansfield N., Hamour S., Habib A.M., Tarzi R., Levy J., Griffith M.,Cairns T., Cook H.T., Pusey C.D., Salama A.D.: Prolonged disease-freeremission following rituximab and low-dose cyclophosphamide therapyfor renal ANCA-associated vasculitis. Nephrol. Dial. Transplant.,2011; 26: 3280-3286
Google Scholar - 65. Marco H., Smith R.M., Jones R.B., Guerry M.J., Catapano F., Burns S.,Chaudhry A.N., Smith K.G., Jayne D.R.: The effect of rituximab therapyon immunoglobulin levels in patients with multisystem autoimmunedisease. BMC Musculoskelet. Disord., 2014; 15: 178
Google Scholar - 66. McAdoo S., Bedi R., Tarzi R., Griffith M., Pusey C., Cairns T.: Ofatumumabfor B cell depletion therapy in ANCA-asociated vasculitis.Nephron, 2015; 129: 111-112 (17th International Vasculitis & ANCAWorkshop)
Google Scholar - 67. McAdoo S.P., Reynolds J., Bhangal G., Smith J., McDaid J.P., TannaA., Jackson W.D., Masuda E.S., Cook H.T., Pusey C.D., Tam F.W.: Spleentyrosine kinase inhibition attenuates autoantibody production andreverses experimental autoimmune GN. J. Am. Soc. Nephrol., 2014;25: 2291-2302
Google Scholar - 68. McGregor J.G., Hogan S.L., Hu Y., Jennette C.E., Falk R.J., NachmanP.H.: Glucocorticoids and relapse and infection rates in anti-neutrophilcytoplasmic antibody disease. Clin. J. Am. Soc. Nephrol., 2012; 7: 240-247
Google Scholar - 69. McGregor J.G., Hogan S.L., Kotzen E.S., Poulton C.J., Hu Y., Negrete-LopezR., Kidd J.M., Katsanos S.L., Bunch D.O., Nachman P.H., FalkR.J.: Rituximab as an immunosuppressant in antineutrophil cytoplasmicantibody-associated vasculitis. Nephrol. Dial. Transplant., 2015;30: 123-131
Google Scholar - 70. Medical Outcomes Study: 36-Item Short Form Survey Instrument.http://www.rand.org/health/surveys_tools/mos/mos_core_36item_survey.html (28.02.2016)
Google Scholar - 71. Metzler C., Miehle N., Manger K., Iking-Konert C., de Groot K.,Hellmich B., Gross W.L., Reinhold-Keller E.: Elevated relapse rate underoral methotrexate versus leflunomide for maintenance of remissionin Wegener’s granulomatosis. Rheumatology, 2007; 46: 1087-1091
Google Scholar - 72. Miloslavsky E.M., Specks U., Merkel P.A., Seo P., Spiera R., LangfordC.A., Hoffman G.S., Kallenberg C.G., St Clair E.W., Tchao N.K., VivianoL., Ding L., Iklé D., Villarreal M., Jepson B., et al.: Rituximab for the treatmentof relapses in antineutrophil cytoplasmic antibody-associatedvasculitis. Arthritis Rheumatol., 2014; 66: 3151-3159
Google Scholar - 73. Miloslavsky E.M., Specks U., Merkel P.A., Seo P., Spiera R., LangfordC.A., Hoffman G.S., Kallenberg C.G., St Clair E.W., Tchao N.K., VivianoL., Ding L., Sejismundo L.P., Mieras K., Iklé D., et al.: Clinical outcomesof remission induction therapy for severe antineutrophil cytoplasmicantibody-associated vasculitis. Arthritis Rheum., 2013; 65: 2441-2449
Google Scholar - 74. Mohammad A.J., Hot A., Arndt F., Moosig F., Guerry M.J., AmudalaN., Smith R., Sivasothy P., Guillevin L., Merkel P.A., Jayne D.R.: Rituximabfor the treatment of eosinophilic granulomatosis with polyangiitis(Churg-Strauss). Ann. Rheum. Dis., 2016; 75: 396-401
Google Scholar - 75. Molloy E.S., Calabrese L.H.: Progressive multifocal leukoencephalopathyassociated with immunosuppressive therapy in rheumaticdiseases: evolving role of biologic therapies. Arthritis. Rheum., 2012;64: 3043-3051
Google Scholar - 76. Moran S., Little M.A.: Renal transplantation in antineutrophilcytoplasmic antibody-associated vasculitis. Curr. Opin. Rheumatol.,2014; 26: 37-41
Google Scholar - 77. Mukhtyar C., Guillevin L., Cid M.C., Dasgupta B., de Groot K., GrossW., Hauser T., Hellmich B., Jayne D., Kallenberg C.G., Merkel P.A., RaspeH., Salvarani C., Scott D.G., Stegeman C., et al.: EULAR recommendationsfor the management of primary small and medium vessel vasculitis.Ann. Rheum. Dis., 2009; 68: 310-317
Google Scholar - 78. Nachman P.H., Denu-Ciocca C.J.: Vasculitides. In.: Current Diagnosisand Treatment, eds.: E.V. Lerma, J.S. Bern, A.R. Nissenson. McGraw-Hill,New York 2008, 265-275
Google Scholar - 79. Nachman P.H., Hogan S.L., Jennette J.C., Falk R.J.: Treatment responseand relapse in antineutrophil cytoplasmic autoantibody-associatedmicroscopic polyangiitis and glomerulonephritis. J. Am. Soc.Nephrol. 1996; 7: 33-39
Google Scholar - 80. Nowack R., Göbel U., Klooker P., Hergesell O., Andrassy K., vander Woude F.J.: Mycophenolate mofetil for maintenance therapy ofWegener’s granulomatosis and microscopic polyangiitis: a pilot studyin 11 patients with renal involvement. J. Am. Soc. Nephrol., 1999;10: 1965-1971
Google Scholar - 81. Ntatsaki E., Carruthers D., Chakravarty K., D’Cruz D., Harper L.,Jayne D., Luqmani R., Mills J., Mooney J., Venning M., Watts R.A.: BSRand BHPR Standards, Guidelines and Audit Working Group. BSR andBHPR guideline for the management of adults with ANCA-associatedvasculitis. Rheumatology, 2014; 53: 2306-2309
Google Scholar - 82. Pagnoux C., Mahr A., Hamidou M.A., Boffa J.J., Ruivard M., DucroixJ.P., Kyndt X., Lifermann F., Papo T., Lambert M., Le Noach J., KhellafM., Merrien D., Puéchal X., Vinzio S., et al.: Azathioprine or methotrexatemaintenance for ANCA-associated vasculitis. N. Engl. J. Med.,2008; 359: 2790-2803
Google Scholar - 83. Pepper R.J., Draibe J., Tchao N., Lim N., Stone J., Specks U., MerkelP., Salama A.D.: The association of serum calprotectin (S100A8/S100A9)levels with disease relapse in PR3-ANCA-associated vasculitis. Nephron,2015; 129: 95-96 (17th International Vasculitis & ANCA Workshop)
Google Scholar - 84. Pepper R.J., Fabre M.A., Pavesio C., Gaskin G., Jones R.B., Jayne D.,Pusey C.D., Salama A.D.: Rituximab is effective in the treatment of refractoryChurg-Strauss syndrome and is associated with diminishedT-cell interleukin-5 production. Rheumatology, 2008; 47: 1104-1105
Google Scholar - 85. Perenyei M., Jayne D.R., Floβmann O.: Gusperimus: immunologicalmechanism and clinical applications. Rheumatology, 2014; 53:1732-1741
Google Scholar - 86. Puéchal X., Pagnoux C., Perrodeau E., Hamidou M., Boffa J., KnydtX., Liferman F., Papo T., Merrien D., Smail A., Delaval P., Hanrotel-SaliouC., Imbert B., Khouatra C., Lambert M.: Granulomatosis with polyangiitisor microscopic polyangiitis: longterm outcomes of the prospectiveWEGENT trial comparing azathioprine vsmethotrexate for remission–maintainance in 126 patients. Nephron, 2015; 129: 80 (17th InternationalVasculitis & ANCA Workshop)
Google Scholar - 87. Pullerits R., Ljevak M., Vikgren J., Bokarewa M.: Off-trial evaluationof the B cell-targeting treatment in the refractory cases of antineutrophilcytoplasmic antibodies (ANCA)-associated vasculitis: long-termfollow-up from a single centre. Scand. J. Immunol., 2012; 76: 411-420
Google Scholar - 88. Rathi M., Sharma A., Nada R.: Renal manifestations. In: Textbookof systemic vasculitis, ed.: A. Sharma. Jaypee Brothers Medical Publishers,New Delhi 2015, 157-163
Google Scholar - 89. Rees F., Yazdani R., Lanyon P.: Long-term follow-up of differentrefractory systemic vasculitides treated with rituximab. Clin. Rheumatol.,2011; 30: 1241-1245
Google Scholar - 90. Rhee E.P., Laliberte K.A., Niles J.L.: Rituximab as maintenance therapy for anti-neutrophil cytoplasmic antibody-associated vasculitis.Clin. J. Am. Soc. Nephrol., 2010; 5: 1394-1400
Google Scholar - 91. Roccatello D., Sciascia S., Rossi D., Alpa M., Naretto C., Russo A.,Menegatti E., Baldovino S.: Long-term effects of rituximab added tocyclophosphamide in refractory patients with vasculitis. Am. J. Nephrol.,2011; 34: 175-180
Google Scholar - 92. Saag K.G., Furst D.E.: Major side effects of systemic glucocorticoids.In: UpToDate, ed.: E.L. Matteson. UpToDate, Waltham, Massachusetts
Google Scholar - 93. Savige J., Gillis D., Benson E., Davies D., Esnault V., Falk R.J., HagenE.C., Jayne D., Jennette J.C., Paspaliaris B., Pollock W., Pusey C., SavageC.O., Silvestrini R., van der Woude F., et al.: International ConsensusStatement on Testing and Reporting of Antineutrophil CytoplasmicAntibodies (ANCA). Am. J. Clin. Pathol., 1999; 111: 507-513
Google Scholar - 94. Schmitt W.H., Hagen E.C., Neumann I., Nowack R., Flores-SuárezL.F., van der Woude F.J.: Treatment of refractory Wegener’s granulomatosiswith antithymocyte globulin (ATG): an open study in 15 patients.Kidney Int., 2004; 65: 1440-1448
Google Scholar - 95. Schönermarck U., Gross W.L., de Groot K.: Treatment of ANCA-associatedvasculitis. Nat. Rev. Nephrol., 2014; 10: 25-36
Google Scholar - 96. Seo P., Min Y.I., Holbrook J.T., Hoffman G.S., Merkel P.A., Spiera R.,Davis J.C., Ytterberg S.R., St Clair E.W., McCune W.J., Specks U., AllenN.B., Luqmani R.A., Stone J.H.: Damage caused by Wegener’s granulomatosisand its treatment: prospective data from the Wegener’sGranulomatosis Etanercept Trial (WGET). Arthritis Rheum., 2005; 52:2168-2178
Google Scholar - 97. Silva F., Specks U., Kalra S., Hogan M.C., Leung N., Sethi S., FervenzaF.C.: Mycophenolate mofetil for induction and maintenanceof remission in microscopic polyangiitis with mild to moderate renalinvolvement – a prospective, open-label pilot trial. Clin. J. Am. Soc.Nephrol., 2010; 5: 445-453
Google Scholar - 98. Sitter T., Schmidt M., Schneider S., Schiffl H.: Differential diagnosisof bacterial infection and inflammatory response in kidney diseasesusing procalcitonin. J. Nephrol. 2002; 15: 297-301
Google Scholar - 99. Smith R.M., Jones R.B., Guerry M.J., Laurino S., Catapano F., ChaudhryA., Smith K.G., Jayne D.R.: Rituximab for remission maintenancein relapsing antineutrophil cytoplasmic antibody-associated vasculitis.Arthritis Rheum., 2012; 64: 3760-3769
Google Scholar - 100. Specks U., Merkel P.A., Seo P., Spiera R., Langford C.A., HoffmanG.S., Kallenberg C.G., St Clair E.W., Fessler B.J., Ding L., Viviano L., TchaoN.K., Phippard D.J., Asare A.L., Lim N., et al.: Efficacy of remission–induction regimens for ANCA-associated vasculitis. N. Engl. J. Med.,2013; 369: 417-427
Google Scholar - 101. Stassen P.M., Tervaert J.W., StegemanC.A.: Induction of remissionin active anti-neutrophil cytoplasmic antibody-associated vasculitiswith mycophenolate mofetil in patients who cannot be treated withcyclophosphamide. Ann. Rheum. Dis., 2007; 66: 798-802
Google Scholar - 102. Statkute L., Oyama Y., Barr W.G., Sufit R., Ho S., Verda L., Loh Y.,Yaung K., Quigley K., Burt R.K.: Autologous non-myeloablative haematopoieticstem cell transplantation for refractory systemic vasculitis.Ann. Rheum. Dis., 2008; 67: 991-997
Google Scholar - 103. Stone J.H., Merkel P.A., Spiera R., Seo P., Langford C.A., HoffmanG.S., Kallenberg C.G., St Clair E.W., Turkiewicz A., Tchao N.K., WebberL., Ding L., Sejismundo L.P., Mieras K., Weitzenkamp D., et al.: Rituximabversus cyclophosphamide for ANCA-associated vasculitis. N. Engl.J. Med., 2010; 363: 221-232
Google Scholar - 104. Suppiah R., Mukhtyar C., Flossmann O., Alberici F., Baslund B.,Batra R., Brown D., Holle J., Hruskova Z., Jayne D.R., Judge A., LittleM.A., Palmisano A., Stegeman C., Tesar V., et al.: A cross-sectional studyof the Birmingham Vasculitis Activity Score version 3 in systemicvasculitis. Rheumatology, 2011; 50: 899-905
Google Scholar - 105. Tang W., Bose B., McDonald S.P., Hawley C.M., Badve S.V., BoudvilleN., Brown F.G., Clayton P.A., Campbell S.B., Peh C.A., Johnson D.W.:The outcomes of patients with ESRD and ANCA-associated vasculitis inAustralia and New Zealand. Clin. J. Am. Soc. Nephrol., 2013; 8: 773-780
Google Scholar - 106. Terrier B., Pagnoux C., Karras A., Khouatra C., Aumaitre O., CohenP., Maurier F., Decaux O., Demurs-Clavel H., Gobert P.: Rituximabversus azathioprine for maintenance in antineutrophil cytoplasmicantibodies (ANCA)-associated vasculitis (MAINRITSAN): Follow-up at 34 months. La Presse Médicale, 2013; 42: 778-779 (16th InternationalVasculitis & ANCA Workshop)
Google Scholar - 107. Thai L.H., Charles P., Resche-Rigon M., Desseaux K., Guillevin L.:Are antiproteinase-3 ANCA a useful marker of granulomatosis withpolyangiitis (Wegener’s) relapses? Results of a retrospective study on 126 patients. Autoimmun. Rev., 2014; 13: 313-318
Google Scholar - 108. Thiel J., Hässler F, Salzer U., Voll R.E., Venhoff N.: Rituximab inthetreatment of refractory or relapsing eosinophilic granulomatosiswithpolyangiitis (Churg-Strauss syndrome). Arthritis Res. Ther.,2013; 15: R133
Google Scholar - 109. Tomasson G., Grayson P.C., Mahr A.D., Lavalley M., Merkel P.A.:Value of ANCA measurements during remission to predict a relapseof ANCA-associated vasculitis – a meta-analysis. Rheumatology, 2012;51: 100-109
Google Scholar - 110. US National Library of Medicine. Clinicaltrials.gov. Belimumabin Remission of VASculitis (BREVAS). http://clinicaltrials.gov/show/NCT01663623 (28.02.2016)
Google Scholar - 111. US National Library of Medicine. Clinicaltrials.gov. ComparisonStudy of Two Rituximab Regimens in the Remission of ANCA AssociatedVasculitis (MAINRITSAN 2). http://clinicaltrials.gov/ct2/show/NCT01731561?term=MAINRITSAN%27&rank=2 (28.02.2016)
Google Scholar - 112. US National Library of Medicine. Clinicaltrials.gov. RituximabVasculitis Maintenance Study (RITAZAREM). http://clinicaltrials.gov/ct2/show/NCT01697267 (28.02.2016)
Google Scholar - 113. van Daalen E., Ferrario F., Noël L.H., Waldherr R. Hagen E.C., BruijnJ.A., Bajema I.M.: Twenty-five years of RENHIS: a history of histopathologicalstudies within EUVAS. Nephrol. Dial. Transplant., 2015; 30: 31-36
Google Scholar - 114. Walsh M., Casian A., Flossmann O., Westman K., Höglund P., PuseyC., Jayne D.R.: Long-term follow-up of patients with severe ANCA-associatedvasculitis comparing plasma exchange to intravenous methylprednisolonetreatment is unclear. Kidney Int., 2013; 84: 397-402
Google Scholar - 115. Walsh M., Chaudhry A., Jayne D.: Long-term follow-up of relapsing/refractoryanti-neutrophil cytoplasm antibody associated vasculitistreated with the lymphocyte depleting antibody alemtuzumab(CAMPATH-1H). Ann. Rheum. Dis. 2008; 67: 1322-1327
Google Scholar - 116. Walsh M., Merkel P.A., Peh C.A., Szpirt W., Guillevin L., Pusey C.D.,De Zoysa J., Ives N., Clark W.F., Quillen K., Winters J.L., Wheatley K., JayneD.: Plasma exchange and glucocorticoid dosing in the treatment ofanti-neutrophil cytoplasm antibody associated vasculitis (PEXIVAS):protocol for a randomized controlled trial. Trials, 2013; 14: 73
Google Scholar - 117. Weiner M., Goh S.M., Mohammad A.J., Hruskova Z., Tanna A.,Bruchfeld A., Selga D., Chocova Z., Westman K., Eriksson P., Pusey C.D.,Tesar V., Salama A.D., Segelmark M.: Outcome and treatment of elderlypatients with ANCA-associated vasculitis. Clin. J. Am. Soc. Nephrol.,2015; 10: 1128-1135
Google Scholar - 118. Wendt M., Gunnarsson I., Bratt J., Bruchfeld A.: Rituximab inrelapsing or refractory ANCA-associated vasculitis: a case series of 16patients. Scand. J. Rheumatol., 2012; 41: 116-119
Google Scholar - 119. Williams M.E., Balogun R.A.: Principles of separation: indicationsand therapeutic targets for plasma exchange. Clin. J. Am. Soc. Nephrol.,2014; 9: 181-190
Google Scholar - 120. Xiao H., Dairaghi D.J., Powers J.P., Ertl L.S., Baumgart T., Wang Y.,Seitz L.C., Penfold M.E., Gan L., Hu P., Lu B., Gerard N.P., Gerard C., SchallT.J., Jaen J.C., Falk R.J.: C5a receptor (CD88) blockade protects againstMPO-ANCA GN. J. Am. Soc. Nephrol., 2014; 25: 225-231
Google Scholar