GLOSA LUB KOMENTARZ PRAWNICZY
Metabolism glikozoaminoglikanów w przebiegu młodzieńczego idiopatycznego zapalenia stawów
Katarzyna Winsz-Szczotka 1 , Łukasz Mencner 1 , Krystyna Olczyk 11. Department of Clinical Chemistry and Laboratory Diagnostics, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Silesia, Sosnowiec, Poland
Opublikowany: 2016-03-04
DOI: 10.5604/17322693.1196355
GICID: 01.3001.0009.6793
Dostępne wersje językowe: pl en
Wydanie: Postepy Hig Med Dosw 2016; 70 : 135-142
Abstrakt
Przypisy
- 1. Agarwal S., Misra R., Aggarwal A.: Synovial fluid RANKL and matrixmetalloproteinase levels in enthesitis related arthritis subtypeof juvenile idiopathic arthritis. Rheumatol. Int., 2009; 29: 907-911
Google Scholar - 2. Angeles-Han S., Prahalad S.: The genetics of juvenile idiopathicarthritis: what is new in 2010? Curr. Rheumatol. Rep., 2010; 12: 87-93
Google Scholar - 3. Angeles-Han S.T., Yeh S., Vogler L.B.: Updates on the risk markersand outcomes of severe juvenile idiopathic arthritis-associateduveitis. Int. J. Clin. Rheumtol., 2013; 8: 10.2217
Google Scholar - 4. Araujo G.R., Fonseca J.E., Fujimura P.T., Cunha-Junior J.P., SilvaC.H., Mourão A.F., Canhão H., Goulart L.R., Gonçalves J., Ueira-VieiraC.: Anti-type II collagen antibodies detection and avidity in patientswith oligoarticular and polyarticular forms of juvenile idiopathicarthritis. Immunol. Lett., 2015: 165: 20-25
Google Scholar - 5. Aslan M., Kasapcopur O., Yasar H., Polat E., Saribas S., Cakan H.,Dirican A., Torun M.M., Arısoy N., Kocazeybek B.: Do infections triggerjuvenile idiopathic arthritis? Rheumatol. Int., 2011; 31: 215-220
Google Scholar - 6. Aspberg A.: The different roles of aggrecan interaction domains.J. Histochem. Cytochem., 2012; 60: 987-996
Google Scholar - 7. Barash J., Goldzweig O.: Possible role of streptococcal infection inflares of juvenile idiopathic arthritis. Arthritis Rheum., 2007; 57: 877-880
Google Scholar - 8. Bartok B., Firestein G.S.: Fibroblast-like synoviocytes: key effectorcells in rheumatoid arthritis. Immunol. Rev., 2010; 233: 233-255
Google Scholar - 9. Behrens E.M., Finkel T.H., Bradfield J.P., Kim C.E., Linton L., CasalunovoT., Frackelton E.C., Santa E., Otieno F.G., Glessner J.T., ChiavacciR.M., Grant S.F., Hakonarson H.: Association of the TRAF1-C5locus on chromosome 9 with juvenile idiopathic arthritis. ArthritisRheum., 2008; 58: 2206-2207
Google Scholar - 10. Berntson L., Nordal E., Fasth A., Aalto K., Herlin T., Nielsen S.,Rygg M., Zak M., Rönnelid J.: Anti-type II collagen antibodies, anti–CCP, IgA RF and IgM RF are associated with joint damage, assessedeight years after onset of juvenile idiopathic arthritis (JIA). Pediatr.Rheumatol. Online J., 2014; 12: 22
Google Scholar - 11. Bozzola E., Pagani S., Meazza C., Cortis E., Lisini D., Laarej K.,Bozzola M.: Changes in growth hormone receptor gene expressionduring therapy in children with juvenile idiopathic arthritis. Horm.Res. Paediatr., 2012; 77: 52-58
Google Scholar - 12. Brescia A.C., Simonds M.M., McCahan S.M., Fawcett P.T., RoseC.D.: The role of transforming growth factor β signaling in fibroblast-like synoviocytes from patients with oligoarticular juvenileidiopathic arthritis: dysregulation of transforming growth factor βsignaling, including overexpression of bone morphogenetic protein4, may lead to a chondrocyte phenotype and may contribute to bonyhypertrophy. Arthritis Rheumatol., 2014; 66: 1352-1362
Google Scholar - 13. Brik R., Rosen I., Savulescu D., Borovoi I., Gavish M., Nagler R.:Salivary antioxidants and metalloproteinases in juvenile idiopathicarthritis. Mol. Med., 2010; 16: 122-128
Google Scholar - 14. Campo G.M., Avenoso A., Campo S., D›Ascola A., Ferlazzo A.M.,Samà D., Calatroni A.: Purified human chondroitin-4-sulfate reducedMMP/TIMP imbalance induced by iron plus ascorbate in humanfibroblast cultures. Cell Biol. Int., 2006; 30: 21-30
Google Scholar - 15. Campo G.M., Avenoso A., D›Ascola A., Campo S., Ferlazzo A.M.,Samà D., Calatroni A.: Purified human plasma glycosaminoglycanslimit oxidative injury induced by iron plus ascorbate in skin fibroblastcultures. Toxicol. In Vitro, 2005; 19: 561-572
Google Scholar - 16. Chabchoub G., Uz E., Maalej A., Mustafa C.A., Rebai A., Mnif M.,Bahloul Z., Farid N.R., Ozcelik T., Ayadi H.: Analysis of skewed X–chromosome inactivation in females with rheumatoid arthritis andautoimmune thyroid diseases. Arthritis Res. Ther., 2009; 11: R106
Google Scholar - 17. Corrado A., Neve A., Maruotti N., Cantatore F.P.: Bone effects ofbiologic drugs in rheumatoid arthritis. Clin. Dev. Immunol., 2013;2013: 945945
Google Scholar - 18. Di Loreto S., Fabiano C., Nigro G.: High prevalence of streptococcalor Epstein-Barr virus infections in children with acute non-septicmonoarthritis. New Microbiol., 2014; 37: 81-86
Google Scholar - 19. Dinarello C.A.: Blocking IL-1 in systemic inflammation. J. Exp.Med., 2005; 201: 1355-1359
Google Scholar - 20. du Souich P., García A.G., Vergés J., Montell E.: Immunomodulatoryand anti-inflammatory effects of chondroitin sulfate. J. Cell.Mol. Med., 2009; 13: 1451-1463
Google Scholar - 21. Duan L., Ma B., Liang Y., Chen J., Zhu W., Li M., Wang D.: Cytokinenetworking of chondrocyte dedifferentiation in vitro and itsimplications for cell-based cartilage therapy. Am. J. Transl. Res.,2015; 7: 194-208
Google Scholar - 22. Duurland C.L., Wedderburn L.R.: Current developments in theuse of biomarkers for juvenile idiopathic arthritis. Curr. Rheumatol.Rep., 2014; 16: 406
Google Scholar - 23. Egea J., García A.G., Verges J., Montell E., López M.G.: Antioxidant,antiinflammatory and neuroprotective actions of chondroitinsulfate and proteoglycans. Osteoarthritis Cartilage, 2010; 18(Suppl. 1): S24-S27
Google Scholar - 24. Ellis J.A., Chavez R.A., Pezic A., Ponsonby A.L., Akikusa J.D., AllenR.C., Munro J.E.: Independent replication analysis of genetic loci withprevious evidence of association with juvenile idiopathic arthritis.Pediatr. Rheumatol. Online J., 2013; 11: 12
Google Scholar - 25. Gao Y., Liu S., Huang J., Guo W., Chen J., Zhang L., Zhao B., PengJ., Wang A., Wang Y., Xu W., Lu S., Yuan M., Guo Q.: The ECM-cell interactionof cartilage extracellular matrix on chondrocytes. Biomed.Res. Int., 2014; 2014: 648459
Google Scholar - 26. Gattorno M., Vignola S., Falcini F., Sabatini F., BuoncompagniA., Simonini G., Picco P., Pistoia V.: Serum and synovial fluidconcentrations of matrix metalloproteinases 3 and its tissue inhibitor 1 in juvenile idiopathic arthritides. J. Rheumatol., 2002;29: 826-831
Google Scholar - 27. Gonzalez B., Larrañaga C., León O., Díaz P., Miranda M., BarríaM., Gaggero A.: Parvovirus B19 may have a role in the pathogenesisof juvenile idiopathic arthritis. J. Rheumatol., 2007; 34: 1336-1340
Google Scholar - 28. György B., Tóthfalusi L., Nagy G., Pásztói M., Géher P., LörincZ., Polgár A., Rojkovich B., Ujfalussy I., Poór G., Pócza P., Wiener Z.,Misják P., Koncz A., Falus A., Buzás E.I.: Natural autoantibodies reactivewith glycosaminoglycans in rheumatoid arthritis. ArthritisRes. Ther., 2008; 10: R110
Google Scholar - 29. Hanyecz A., Olasz K., Tarjanyi O., Nemeth P., Mikecz K., GlantT.T., Boldizsar F.: Proteoglycan aggrecan conducting T cell activationand apoptosis in a murine model of rheumatoid arthritis. Biomed.Res. Int., 2014; 2014: 942148
Google Scholar - 30. Hollenbach J.A., Thompson S.D., Bugawan T.L., Ryan M., SudmanM., Marion M., Langefeld C.D., Thomson G., Erlich H.A., Glass D.N.:Juvenile idiopathic arthritis and HLA class I and class II interactionsand age-at-onset effects. Arthritis Rheum., 2010; 62: 1781-1791
Google Scholar - 31. Huang J.L.: New advances in juvenile idiopathic arthritis. ChangGung Med. J., 2012; 35: 1-14
Google Scholar - 32. Jura-Półtorak A., Komosinska-Vassev K., Kotulska A., KucharzE.J., Klimek K., Kopec-Medrek M., Olczyk K.: Alterations of plasmaglycosaminoglycan profile in patients with rheumatoid arthritis inrelation to disease activity. Clin. Chim. Acta, 2014; 433: 20-27
Google Scholar - 33. Kahn P.: Juvenile idiopathic arthritis: an update for the clinician.Bull. NYU Hosp. Jt. Dis., 2012; 70: 152-166
Google Scholar - 34. Kalinina Ayuso V., Makhotkina N., van Tent-Hoeve M., de Groot–Mijnes J.D., Wulffraat N.M., Rothova A., de Boer J.H.: Pathogenesisof juvenile idiopathic arthritis associated uveitis: the known andunknown. Surv. Ophthalmol., 2014; 59: 517-531
Google Scholar - 35. Kaminiarczyk D., Adamczyk K., Niedziela M.: Proinflammatoryfactors in children with juvenile idiopathic arthritis. Reumatologia,2010; 48: 62-65
Google Scholar - 36. Kamphuis S., Hrafnkelsdóttir K., Klein M.R., de Jager W., HaverkampM.H., van Bilsen J.H., Albani S., Kuis W., Wauben M.H., PrakkenB.J.: Novel self-epitopes derived from aggrecan, fibrillin, and matrixmetalloproteinase-3 drive distinct autoreactive T-cell responsesin juvenile idiopathic arthritis and in health. Arthritis Res. Ther.,2006; 8: R178
Google Scholar - 37. Kapoor M., Martel-Pelletier J., Lajeunesse D., Pelletier J.P., FahmiH.: Role of proinflammatory cytokines in the pathophysiologyof osteoarthritis. Nat. Rev. Rheumatol., 2011; 7: 33-42
Google Scholar - 38. Kitaura H., Kimura K., Ishida M., Kohara H., Yoshimatsu M.,Takano-Yamamoto T.: Immunological reaction in TNF-α-mediatedosteoclast formation and bone resorption in vitro and in vivo. Clin.Dev. Immunol., 2013; 2013: 181849
Google Scholar - 39. Klein T., Bischoff R.: Physiology and pathophysiology of matrixmetalloproteases. Amino Acids, 2011; 41: 271-290
Google Scholar - 40. Kontny E.: Pathogenesis of juvenile idiopathic arthritis. In: Juvenileidiopathic arthritis – not only news, ed.: Rutkowska-Sak L.Ter-Media Poznań 2014, 17-56
Google Scholar - 41. Kozireva S.V., Zestkova J.V., Mikazane H.J., Kadisa A.L., KakurinaN.A., Lejnieks A.A., Danilane I.N., Murovska M.F.: Incidence andclinical significance of parvovirus B19 infection in patients withrheumatoid arthritis. J. Rheumatol., 2008; 35: 1265-1270
Google Scholar - 42. Lambert N.C.: The price of silence. Arthritis Rheum., 2009; 60:3164-3167
Google Scholar - 43. Lauder R.M.: Chondroitin sulfate: a complex molecule with potentialimpacts on a wide range of biological systems. Complement.Ther. Med., 2009; 17: 56-62
Google Scholar - 44. Lin Y.T., Wang C.T., Gershwin M.E., Chiang B.L.: The pathogenesisof oligoarticular/polyarticular vs systemic juvenile idiopathicarthritis. Autoimmun. Rev., 2011; 10: 482-489
Google Scholar - 45. Lipińska J., Lipińska S., Stańczyk J., Sarniak A., Przymińska velPrymont A., Kasielski M., Smolewska E.: Reactive oxygen speciesand serum antioxidant defense in juvenile idiopathic arthritis. Clin.Rheumatol., 2015; 34: 451-456
Google Scholar - 46. Lipińska J., Smolewska E., Brózik H., Stańczyk J.: Immunologicalmarkers in diagnosing and prognosing of JIA and RA. Allergy AsthmaImmunology, 2005; 10: 117-124
Google Scholar - 47. Löffek S., Schilling O., Franzke C.W.: Series „matrix metalloproteinasesin lung health and disease”: Biological role of matrix metalloproteinases:a critical balance. Eur. Respir. J., 2011; 38: 191-208
Google Scholar - 48. Macaubas C., Nguyen K., Milojevic D., Park J.L., Mellins E.D.: Oligoarticularand polyarticular JIA: epidemiology and pathogenesis.Nat. Rev. Rheumatol., 2009; 5: 616-626
Google Scholar - 49. Martel-Pelletier J., Kwan Tat S., Pelletier J.P.: Effects of chondroitinsulfate in the pathophysiology of the osteoarthritic joint: anarrative review. Osteoarthritis Cartilage, 2010; 18 (Suppl. 1): S7-S11
Google Scholar - 50. Matsuyama T.: Tissue inhibitor of metalloproteinases-1 andmatrix metalloproteinase-3 in Japanese healthy children and in Kawasakidisease and their clinical usefulness in juvenile rheumatoidarthritis. Pediatr. Int., 1999; 41: 239-245
Google Scholar - 51. Mierzchała M., Lipińska-Gediga M., Durek G.: The role of LBP intransduction of signal induced by LPS and in modulation of immunesystem response. Adv. Clin. Exp. Med., 2006; 15: 127-134
Google Scholar - 52. Montaseri A., Busch F., Mobasheri A., Buhrmann C., Aldinger C.,Rad J.S., Shakibaei M.: IGF-1 and PDGF-bb suppress IL-1β-inducedcartilage degradation through down-regulation of NF-κB signaling:involvement of Src/PI-3K/AKT pathway. PLoS One, 2011; 6: e28663
Google Scholar - 53. Mor A., Abramson S.B., Pillinger M.H.: The fibroblast-like synovialcell in rheumatoid arthritis: a key player in inflammation andjoint destruction. Clin. Immunol., 2005; 115: 118-128
Google Scholar - 54. Moradi A., Amin R.M., Thorne J.E.: The role of gender in juvenileidiopathic arthritis-associated uveitis. J. Ophthalmol., 2014;2014: 461078
Google Scholar - 55. Nikitovic D., Corsini E., Kouretas D., Tsatsakis A., Tzanakakis G.:ROS-major mediators of extracellular matrix remodeling during tumorprogression. Food Chem. Toxicol., 2013; 61: 178-186
Google Scholar - 56. Nikitovic D., Zafiropoulos A., Katonis P., Tsatsakis A., TheocharisA.D., Karamanos N.K., Tzanakakis G.N.: Transforming growthfactor-β as a key molecule triggering the expression of versicanisoforms v0 and v1, hyaluronan synthase-2 and synthesis of hyaluronanin malignant osteosarcoma cells. IUBMB Life, 2006; 58: 47-53
Google Scholar - 57. Noss E.H., Brenner M.B.: The role and therapeutic implicationsof fibroblast-like synoviocytes in inflammation and cartilage erosionin rheumatoid arthritis. Immunol. Rev., 2008; 223: 252-270
Google Scholar - 58. Oberle E.J., Harris J.G., Verbsky J.W.: Polyarticular juvenile idiopathicarthritis – epidemiology and management approaches. Clin.Epidemiol., 2014; 6: 379-393
Google Scholar - 59. Parsons B.J.: Oxidation of glycosaminoglycans by free radicalsand reactive oxidative species: a review of investigative methods.Free Radic. Res., 2015; 49: 618-632
Google Scholar - 60. Peake N.J., Foster H.E., Khawaja K., Cawston T.E., Rowan A.D.:Assessment of the clinical significance of gelatinase activity in patientswith juvenile idiopathic arthritis using quantitative proteinsubstrate zymography. Ann. Rheum. Dis., 2006; 65: 501-507
Google Scholar - 61. Peake N.J., Khawaja K., Myers A., Jones D., Cawston T.E., RowanA.D., Foster H.E.: Levels of matrix metalloproteinase (MMP)-1in paired sera and synovial fluids of juvenile idiopathic arthritispatients: relationship to inflammatory activity, MMP-3 and tissueinhibitor of metalloproteinases-1 in a longitudinal study. Rheumatology,2005; 44: 1383-1389
Google Scholar - 62. Petty R.E., Southwood T.R., Manners P., Baum J., Glass D.N.,Goldenberg J., He X., Maldonado-Cocco J., Orozco-Alcala J., PrieurA.M., Suarez-Almazor M.E., Woo P.: International League of Associationsfor Rheumatology classification of juvenile idiopathicarthritis: second revision, Edmonton, 2001. J. Rheumatol., 2004;31: 390-392
Google Scholar - 63. Postepski J., Opoka-Winiarska V., Kozioł-Montewka M., KorobowiczA., Tuszkiewicz-Misztal E.: Role of mycoplasma pneumoniaeinfection in aetiopathogenesis of juvenile idiopatic arthritis. Med.Wieku Rozwoj., 2003; 7: 271-277
Google Scholar - 64. Prahalad S., Glass D.N.: A comprehensive review of the geneticsof juvenile idiopathic arthritis. Pediatr. Rheumatol. Online J.,2008; 6: 11
Google Scholar - 65. Prahalad S., Hansen S., Whiting A., Guthery S.L., Clifford B.,McNally B., Zeft A.S., Bohnsack J.F., Jorde L.B.: Variants in TNFAIP3,STAT4, and C12orf30 loci associated with multiple autoimmune diseasesare also associated with juvenile idiopathic arthritis. ArthritisRheum., 2009; 60: 2124-2130
Google Scholar - 66. Prakken B., Albani S., Martini A.: Juvenile idiopathic arthritis.Lancet, 2011; 377: 2138-2149
Google Scholar - 67. Ravelli A., Martini A.: Juvenile idiopathic arthritis. Lancet, 2007;369: 767-778
Google Scholar - 68. Rigante D., Bosco A., Esposito S.: The etiology of juvenile idiopathicarthritis. Clin. Rev. Allergy Immunol., 2015; 49: 253-261
Google Scholar - 69. Riise Ø.R., Lee A., Cvancarova M., Handeland K.S., Wathne K.O.,Nakstad B., Gaustad P., Flatø B.: Recent-onset childhood arthritis -association with Streptococcus pyogenes in a population-based study.Rheumatology, 2008; 47: 1006-1011
Google Scholar - 70. Rosengren S., Corr M., Boyle D.L.: Platelet-derived growth factorand transforming growth factor beta synergistically potentiateinflammatory mediator synthesis by fibroblast-like synoviocytes.Arthritis Res. Ther., 2010; 12: R65
Google Scholar - 71. Sarzi-Puttini P., Atzeni F., Schölmerich J., Cutolo M., Straub R.H.:Anti-TNF antibody treatment improves glucocorticoid induced insulin-like growth factor 1 (IGF1) resistance without influencing myoglobinand IGF1 binding proteins 1 and 3. Ann. Rheum. Dis., 2006;65: 301-305
Google Scholar - 72. Saurenmann R.K., Rose J.B., Tyrrell P., Feldman B.M., Laxer R.M.,Schneider R., Silverman E.D.: Epidemiology of juvenile idiopathicarthritis in a multiethnic cohort: ethnicity as a risk factor. ArthritisRheum., 2007; 56: 1974-1984
Google Scholar - 73. Scardapane A., Ferrante R., Nozzi M., Savino A., Antonucci I.,Dadorante V., Balsamo M., Stuppia L., Chiarelli F., Breda L.: TNF-αgene polymorphisms and juvenile idiopathic arthritis: influence ondisease outcome and therapeutic response. Semin. Arthritis Rheum.;2015; 45: 35-41
Google Scholar - 74. Semeraro F., Arcidiacono B., Nascimbeni G., Angi M., Parolini B.,Costagliola C.: Anti-TNF therapy for juvenile idiopathic arthritis-relateduveitis. Drug Des. Devel. Ther., 2014; 8: 341-348
Google Scholar - 75. Sivan S.S., Wachtel E., Roughley P.: Structure, function, agingand turnover of aggrecan in the intervertebral disc. Biochim. Biophys.Acta, 2014; 1840: 3181-3189
Google Scholar - 76. Straub R.H., Dhabhar F.S., Bijlsma J.W., Cutolo M.: How psychologicalstress via hormones and nerve fibers may exacerbate rheumatoidarthritis. Arthritis Rheum., 2005; 52: 16-26
Google Scholar - 77. Struglics A., Lohmander L.S., Last K., Akikusa J., Allen R., FosangA.J.: Aggrecanase cleavage in juvenile idiopathic arthritispatients is minimally detected in the aggrecan interglobular domainbut robust at the aggrecan C-terminus. Arthritis Rheum.,2012; 64: 4151-4161
Google Scholar - 78. Taylor-Robinson D., Thomas B., Rooney M.: Association of Chlamydiapneumoniae with chronic juvenile arthritis. Eur. J. Clin. Microbiol.Infect. Dis., 1998; 17: 211-212
Google Scholar - 79. Todome Y., Ohkuni H., Mizuse M., Furuya M., Fujikawa S., TanakaS., Watanabe N., Fujii K., Zabriskie J.B.: Detection of antibodies againststreptococcal peptidoglycan and the peptide subunit (synthetictetra-D-alanyl-bovine serum albumin complex) in rheumatic-diseases.Int. Arch. Allergy Immunol., 1992; 97: 301-307
Google Scholar - 80. Tuchocka A., Puszczewicz M.: The role of tocilizumab in thetreatment of rheumatoid arthritis. Reumatologia, 2008; 46: 140-150
Google Scholar - 81. Tugal-Tutkun I., Quartier P., Bodaghi B.: Disease of the year:juvenile idiopathic arthritis-associated uveitis – classification anddiagnostic approach. Ocul. Immunol. Inflamm., 2014; 22: 56-63
Google Scholar - 82. Uz E., Mustafa C., Topaloglu R., Bilginer Y., Dursun A., KasapcopurO., Ozen S., Bakkaloglu A., Ozcelik T.: Increased frequency ofextremely skewed X chromosome inactivation in juvenile idiopathicarthritis. Arthritis Rheum., 2009; 60: 3410-3412
Google Scholar - 83. Vallières M., du Souich P.: Modulation of inflammation by chondroitinsulfate. Osteoarthritis Cartilage, 2010; 18 (Suppl. 1): S1-S6
Google Scholar - 84. Verbruggen G.: Chondroprotective drugs in degenerative jointdiseases. Rheumatology, 2006; 45: 129-138
Google Scholar - 85. Visvanathan S., Wagner C., Marini J.C., Lovell D.J., Martini A., PettyR., Cuttica R., Woo P., Espada G., Gattorno M., Apaz M.T., BaildamE., Fasth A., Gerloni V., Lahdenne P., et al.: Paediatric RheumatologyINternational Trials Organization (PRINTO); Pediatric RheumatologyCollaborative Study Group (PRCSG). The effect of infliximab plusmethotrexate on the modulation of inflammatory disease markers injuvenile idiopathic arthritis: analyses from a randomized, placebo–controlled trial. Pediatr. Rheumatol. Online J., 2010; 8: 24
Google Scholar - 86. Viswanath V., Myles A., Dayal R., Aggarwal A.: Levels of serummatrix metalloproteinase-3 correlate with disease activity in theenthesitis-related arthritis category of juvenile idiopathic arthritis.J. Rheumatol., 2011; 38: 2482-2487
Google Scholar - 87. Volpi N.: Anti-inflammatory activity of chondroitin sulfate: newfunctions from an old natural macromolecule. Inflammopharmacology,2011; 19: 299-306
Google Scholar - 88. Vynios D.H.: Metabolism of cartilage proteoglycans in healthand disease. Biomed. Res. Int., 2014; 2014: 452315
Google Scholar - 89. Wang Y., Pei F., Wang X., Sun Z., Hu C., Dou H.: Meta-analysis:diagnostic accuracy of anti-cyclic citrullinated peptide antibody forjuvenile idiopathic arthritis. J. Immunol. Res., 2015; 2015: 915276
Google Scholar - 90. Winsz-Szczotka K., Komosińska-Vassev K., Kuźnik-Trocha K.,Gruenpeter A., Lachór-Motyka I., Olczyk K.: Influence of proteolytic-antiproteolytic enzymes and prooxidative-antioxidative factorson proteoglycan alterations in children with juvenile idiopathic arthritis.Clin. Biochem., 2014; 47: 829-834
Google Scholar - 91. Winsz-Szczotka K., Komosińska-Vassev K., Kuźnik-Trocha K., OlczykK.: Antioxidant activity and structural modifications of serumchondroitin sulfate in Graves’ disease. Clin. Biochem., 2014; 47: 19-24
Google Scholar - 92. Winsz-Szczotka K., Komosińska-Vassev K., Kuźnik-Trocha K., SiwiecA., Żegleń B., Olczyk K.: Circulating keratan sulfate as a markerof metabolic changes of cartilage proteoglycan in juvenile idiopathicarthritis; influence of growth factors as well as proteolyticand prooxidative agents on aggrecan alterations. Clin. Chem. Lab.Med., 2015; 53: 291-297
Google Scholar - 93. Winsz-Szczotka K., Kuźnik-Trocha K., Komosińska-Vassev K.,Wisowski G., Gruenpeter A., Lachór-Motyka I., Żegleń B., LemskiW., Olczyk K.: Plasma and urinary glycosaminoglycans in the courseof juvenile idiopathic arthritis. Biochem. Biophys. Res. Commun.,2015; 458: 639-643
Google Scholar - 94. Wojdasiewicz P., Poniatowski Ł.A., Szukiewicz D.: The role of inflammatoryand anti-inflammatory cytokines in the pathogenesis ofosteoarthritis. Mediators Inflamm., 2014; 2014: 561459
Google Scholar - 95. Yao T.C., Kuo M.L., See L.C., Ou L.S., Lee W.I., Chan C.K., Huang J.L.:RANTES and monocyte chemoattractant protein 1 as sensitive markersof disease activity in patients with juvenile rheumatoid arthritis:a six-year longitudinal study. Arthritis Rheum., 2006; 54: 2585-2593
Google Scholar