Abstrakt

Przypisy

• 1. Alakurtti S., Mӓkelӓ T., Koskimies S., Yli- Kauhaluoma J.: Pharmacologicalproperties of the ubiquitous natural product betulin.Eur. J. Pharm. Sci., 2006; 29: 1-13
  Google Scholar
• 2. Bhatia S., Tykodi S.S., Thompson J.A.: Treatment of metastaticmelanoma: an overview. Oncology, 2009; 23: 488-496
  Google Scholar
• 3. Bori I.D., Hung H.Y., Qian K., Chen C.H., Morris-Natschke S.L.,Lee K.H.: Anti-AIDS agents 88. Anti-HIV conjugates of betulin andbetulinic acid with AZT prepared via click chemistry. TetrahedronLett., 2012; 53: 1987-1989
  Google Scholar
• 4. Boryczka S., Bębenek E., Wietrzyk J., Kempińska K., JastrzębskaM., Kusz J., Nowak M.: Synthesis, structure and cytotoxic activity ofnew acetylenic derivatives of betulin. Molecules, 2013; 18: 4526-4543
  Google Scholar
• 5. Boryczka S., Mól W., Milczarek M., Wietrzyk J., Bębenek E.: Synthesisand in vitro antiproliferative activity of novel (4-chloro- and 4- acyloxy-2-butynyl)thioquinolines.Med. Chem. Res., 2011; 20: 1402-1410
  Google Scholar
• 6. Bradford M.M.: A rapid and sensitive method for the quantitationof microgram quantities of protein utilizing the principle ofprotein-dye binding. Anal. Biochem., 1976; 72: 248-254
  Google Scholar
• 7. Chen Y., Sun R., Wang B.: Monolayer behavior of binary systemsof betulinic acid and cardiolipin: thermodynamic analyses of Langmuirmonolayers and AFM study of Langmuir-Blodgett monolayers.J. Colloid Interface Sci., 2011; 353: 294-300
  Google Scholar
• 8. Dehelean C.A., Soica C., Ledeti I., Aluas M., Zupko I., Luscan A.,Cinta-Pinzaru S., Munteanu M.: Study of the betulin enriched birchbark extracts effects on human carcinoma cells and ear inflammation.Chem. Cent. J., 2012; 6: 137
  Google Scholar
• 9. Drag M., Surowiak P., Drag-Zalesinska M., Dietel M., Lage H., OleksyszynJ.: Comparision of the cytotoxic effects of birch bark extract,betulin and betulinic acid towards human gastric carcinoma andpancreatic carcinoma drug-sensitive and drug-resistant cell lines.Molecules, 2009; 14: 1639-1651
  Google Scholar
• 10. Eggermont A.M., Robert C.: New drugs in melanoma: it’s a wholenew world. Eur. J. Cancer, 2011; 47: 2150-2157
  Google Scholar
• 11. Erdmann F., Lortet-Tieulent J., Schüz J., Zeeb H., Greinert R.,Breitbart E.W., Bray F.: International trends in the incidence of malignantmelanoma 1953-2008 – are recent generations at higher orlower risk? Int. J. Cancer, 2013; 132: 385-400
  Google Scholar
• 12. Ferlay J., Steliarova-Foucher E., Lortet-Tieulent J., Rosso S., CoeberghJ.W., Comber H., Forman D., Bray F.: Cancer incidence andmortality patterns in Europe: estimates for 40 countries in 2012.Eur. J. Cancer, 2013; 49: 1374-1403
  Google Scholar
• 13. Gauthier C., Legault J., Lavoie S., Rondeau S., Tremblay S., PichetteA.: Synthesis and cytotoxicity of bidesmosidic betulin andbetulinic acid saponins. J. Nat. Prod., 2009; 72: 72-81
  Google Scholar
• 14. Hata K., Hori K., Takahashi S.: Differentiation- and apoptosisinducingactivities by pentacyclic triterpenes on a mouse melanomacell line. J. Nat. Prod., 2002; 65: 645-648
  Google Scholar
• 15. Jäger S., Laszczyk M.N., Scheffler A.: A preliminary pharmacokineticstudy of betulin, the main pentacyclic triterpene fromextract of outer bark of birch (Betulae alba cortex). Molecules, 2008;13: 3224-3235
  Google Scholar
• 16. Jäger S., Trojan H., Kopp T., Laszczyk M.N., Scheffler A.: Pentacyclictriterpene distribution in various plants – rich sources for a newgroup of multi-potent plant extracts. Molecules, 2009; 14: 2016-2031
  Google Scholar
• 17. Joshua A.M.: Melanoma prevention: are we doing enough? ACanadian perspective. Curr. Oncol., 2012; 19: e462-e467
  Google Scholar
• 18. Laszczyk M.N.: Pentacyclic triterpenes of the lupane, oleananeand ursane group as tools in cancer therapy. Planta Med., 2009; 75:1549-1560
  Google Scholar
• 19. Li Y., He K., Huang Y., Zheng D., Gao C., Cui L., Jin Y.H.: Betulininduces mitochondrial cytochrome c release associated apoptosisin human cancer cells. Mol. Carcinog., 2010; 49: 630-640
  Google Scholar
• 20. Li Y., Shen J.T., Gao C., Li Q., Jin Y.H.: Caspase-9 activation – criticalfor betulin-induced apoptosis of human hepatoma cells. Chem.Res. Chin. Univ., 2010; 26: 792-797
  Google Scholar
• 21. MacKie R.M., Hauschild A., Eggermont A.M.: Epidemiology of invasivecutaneous melanoma. Ann. Oncol., 2009, 20 (Suppl. 6): vi1-vi7
  Google Scholar
• 22. Muceniece R., Saleniece K., Riekstina U., Krigere L., Tirzitis G.,Ancans J.: Betulin binds to melanocortin receptors and antagonizesα-melanocyte stimulating hormone induced cAMP generationin mouse melanoma cells. Cell Biochem. Funct., 2007; 25: 591-596
  Google Scholar
• 23. Mukherjee R., Kumar V., Srivastava S.K., Agarwal S.K., BurmanA.C.: Betulinic acid derivatives as anticancer agents: structure activityrelationship. Anticancer Agents Med. Chem., 2006; 6: 271-279
  Google Scholar
• 24. Mullauer F.B., Kessler J.H., Medema J.P.: Betulin is a potent antitumoragent that is enhanced by cholesterol. PLoS One, 2009; 4: e1
  Google Scholar
• 25. Patočka J.: Biologically active pentacyclic triterpenes and theircurrent medicine signification. J. Appl. Biomed., 2003; 1: 7-12
  Google Scholar
• 26. Porter A.G., Jänicke R.U.: Emerging roles of caspase-3 in apoptosis.Cell Death Differ., 1999; 6: 99-104
  Google Scholar
• 27. Pyo J.S., Roh S.H., Kim D.K., Lee J.G., Lee Y.Y., Hong S.S., KwonS.W., Park J.H.: Anti-cancer effect of betulin on a human lung cancercell line: a pharmacoproteomic approach using 2 D SDS PAGEcoupled with nano-HPLC tandem mass spectrometry. Planta Med.,2009; 75: 127-131
  Google Scholar
• 28. Quinn T., Zhang X., Miao Y.: Targeted melanoma imaging andtherapy with radiolabeled alpha-melanocyte stimulating hormonepeptide analogues. G. Ital. Dermatol. Venereol., 2010; 145: 245-258
  Google Scholar
• 29. Soica C., Dehelean C., Danciu C., Wang H.M., Wenz G., Ambrus R.,Bojin F., Anghel M.: Betulin complex in γ-cyclodextrin derivatives:properties and antineoplasic activities in in vitro and in vivo tumormodels. Int. J. Mol. Sci., 2012; 13: 14992-15011
  Google Scholar
• 30. Suresh C., Zhao H., Gumbs A., Chetty C.S., Bose H.S.: New ionicderivatives of betulinic acid as highly potent anti-cancer agents.Bioorg. Med. Chem. Lett., 2012; 22: 1734-1738
  Google Scholar
• 31. Tan Y., Yu R., Pezzuto J.M.: Betulinic acid-induced programmedcell death in human melanoma cells involves mitogen-activated proteinkinase activation. Clin. Cancer Res., 2003; 9: 2866-2875
  Google Scholar
• 32. Viola J.R., Rafael D.F., Wagner E., Besch R., Ogris M.: Gene therapyfor advanced melanoma: selective targeting and therapeutic nucleicacids. J. Drug Deliv., 2013; 2013: 897348
  Google Scholar

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